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2010 Publications

Zhang MY, Borges AR, Ptak RG, Wang Y, Dimitrov AS, Alam SM, Wieczorek L, Bouma P, Fouts T, Jiang S, Polonis VR, Haynes BF, Quinnan GV, Montefiori DC, Dimitrov, DS. Potent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1. MAbs. 2010 May 5;2(3).

Matyas GR, Wieczorek L, Bansal D, Chenine AL, Sanders-Buell E, Tovanabutra S, Kim JH, Polonis V, Alving CR. Inhibition of HIV-1 infection of peripheral blood mononuclear cells by a monoclonal antibody that binds to phosphoinositides and induces secretion of β-chemokines. Biochem Biophys Res Commun. 2010 Nov 26;402(4):808-12.

Kijak GH, Tovanabutra S, Beyrer C, Sanders-Buell EE, Arroyo MA, Robb ML, Michael NL, McCutchan FE, Kim JH. RecDraw: A Software Package for the Representation of HIV-1 Recombinant Structures. AIDS Res Hum Retroviruses. 2010  Oct 21. [Epub ahead of print]

Paris RM, Kim JH, Robb ML, Michael NL. Prime-boost  immunization with poxvirus or adenovirus vectors as a strategy to develop a protective vaccine for HIV-1. Expert Rev Vaccines. 2010 Sep;9(9):1055-69. Review.

Koehler RN, Walsh AM, Saathoff E, Tovanabutra S, Arroyo MA, Currier JR,  Maboko L, Hoelsher M, Robb ML, Michael NL, McCutchan FE, Kim JH, Kijak GH. Class I HLA-A*7401 is associated with protection from HIV-1 acquisition and disease  progression in Mbeya, Tanzania. J Infect Dis. 2010 Nov 15;202(10):1562-6. Epub 2010 Oct 5.

Rao M, Peachman KK, Li Q, Matyas GR, Shivachandra SB, Borschel R, Morthole VI, Fernandez-Prada C, Alving CR, Rao VB. Highly effective generic adjuvant systems for orphan or poverty-related vaccines. Vaccine. 2010 Nov 26. [Epub ahead of print] PubMed

Peachman KK, Wieczorek L, Polonis VR, Alving CR, Rao M. The effect of sCD4 on the binding and accessibility of HIV-1 gp41 MPER epitopes to human monoclonal antibodies. Virology. 2010 Dec 20;408(2):213-23. Epub 2010 Oct 20.

Boonnak K, Dambach KM, Donofrio GC, Tassaneetrithep B, Marovich MA. Cell Type Specificity and Host Genetic Polymorphisms Influence Antibody Dependent Enhancement of Dengue Virus Infection. J Virol. 2010 Dec 1. [Epub ahead of print]

Halstead SB, Mahalingam S, Marovich MA, Ubol S, Mosser DM. Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes. Lancet Infect Dis. 2010 Oct;10(10):712-22. Review.

Steers NJ, Currier JR, Kijak GH, di Targiani RC, Saxena A, Marovich MA, Kim JH, Michael NL, Alving CR, Rao M. Cell Type-Specific Proteasomal Processing of HIV-1 Gag-p24 Results in an Altered Epitope Repertoire. J Virol. 2010 Nov 24. [Epub ahead of print]

Currier JR, Ngauy V, de Souza MS, Ratto-Kim S, Cox JH, Polonis VR, Earl P, Moss B, Peel S, Slike B, Sriplienchan S, Thongcharoen P, Paris RM, Robb ML, Kim J, Michael NL, Marovich MA. Phase I Safety and Immunogenicity Evaluation of MVA-CMDR, a Multigenic, Recombinant Modified Vaccinia Ankara-HIV-1 Vaccine Candidate. PLoS One. 2010 Nov 15;5(11):e13983. PubMed PMID: 21085591.

Brown BK, Cox J, Gillis A, Vancott TC, Marovich M, Milazzo M, Antonille TS, Wieczorek L, McKee KT, Metcalfe K, Mallory RM, Birx D, Polonis VR, Robb ML. Phase I Study of Safety and Immunogenicity of an Escherichia coli-Derived Recombinant Protective Antigen (rPA) Vaccine to Prevent Anthrax in Adults. PLoS One. 2010 Nov 5;5(11):e13849. PubMed PMID: 21079762; PubMed Central PMCID: PMC2974626.

Rosa Borges A, Wieczorek L, Johnson B, Benesi AJ, Brown BK, Kensinger RD, Krebs FC, Wigdahl B, Blumenthal R, Puri A, McCutchan FE, Birx DL, Polonis VR, Schengrund CL. Multivalent dendrimeric compounds containing carbohydrates expressed on immune cells inhibit infection by primary isolates of HIV-1. Virology. 2010 Dec 5;408(1):80-8. Epub 2010 Sep 28. PubMed PMID: 20880566; PubMed Central PMCID: PMC2966527.

Janetzki S, Price L, Britten CM, van der Burg SH, Caterini J, Currier JR, Ferrari G, Gouttefangeas C, Hayes P, Kaempgen E, Lennerz V, Nihlmark K, Souza V, Hoos A. Performance of serum-supplemented and serum-free media in IFNgamma Elispot Assays for human T cells. Cancer Immunol Immunother. 2010 Apr;59(4):609-18. Epub 2009 Nov 6. PubMed PMID: 19894047; PubMed Central PMCID: PMC2813531.

Olemukan RE, Eller LA, Ouma BJ, Etonu B, Erima S, Naluyima P, Kyabaggu D, Cox JH, Sandberg JK, Wabwire-Mangen F, Michael NL, Robb ML, de Souza MS, Eller MA. Quality Monitoring of HIV-1 Infected and Uninfected Peripheral Blood Mononuclear Cell Samples in a Resource Limited Setting. Clin Vaccine Immunol. 2010 Mar 3. [Epub ahead of print] PubMed PMID: 20200187.

Olemukan RE, Eller LA, Ouma BJ, Etonu B, Erima S, Naluyima P, Kyabaggu D, Cox   JH, Sandberg JK, Wabwire-Mangen F, Michael NL, Robb ML, de Souza MS, Eller MA. Quality monitoring of HIV-1-infected and uninfected peripheral blood mononuclear cell  samples  in a resource-limited setting. Clin Vaccine Immunol. 2010 Jun;17(6):910-8.

Vahey MT, Wang Z, Kester KE, Cummings J, Heppner DG Jr, Nau ME, Ofori-Anyinam O, Cohen J, Coche T, Ballou WR, Ockenhouse CF. Expression of genes associated with immunoproteasome processing of major histocompatibility complex peptides is  indicative of protection with adjuvanted RTS,S malaria vaccine. J Infect Dis. 2010 Feb 15;201(4):580-9. 

Aboud S, Nilsson C, Karlén K, Marovich M, Wahren B, Sandström E, Gaines H, Biberfeld G, Godoy-Ramirez K. Strong HIV-Specific CD4+ and CD8+ T lymphocyte proliferative responses in healthy individuals immunized with a HIV-1 DNA vaccineand boosted with HIV-1 recombinant Modified Vaccinia virus Ankara (MVA). Clin Vaccine Immunol. 2010 May 12.

Koehler RN, Walsh AM, Sanders-Buell EE, Eller LA, Eller M, Currier JR, Bautista CT, Wabwire-Mangen F, Hoelscher M, Maboko L, Kim J, Michael NL, Robb ML, McCutchan FE, Kijak GH. High-throughput high-resolution class I  HLA  genotyping in East Africa. PLoS One. 2010 May 20;5(5):e10751. 

Cork DJ, Lembark S, Tovanabutra S, Robb ML, Kim JH. W-curve alignments for HIV-1 genomic comparisons. PLoS One. 2010 Jun 1;5(6):e10829

Aboud S, Nilsson C, Karlen K, Marovich M, Wahren B, Sandstr√∂m E, Gaines H, Biberfeld G, Godoy-Ramirez K. Strong HIV-specific CD4+ and CD8+ T-lymphocyte Proliferative responses in healthy individuals immunized with an HIV-1 DNA Vaccine and boosted with recombinant modified vaccinia virus  ankara expressing HIV-1 genes. Clin Vaccine Immunol. 2010 Jul; 17(7): 1124-31. Epub 2010 May 12.

Saathoff E, Pritsch M, Geldmacher C, Hoffmann O, Koehler RN, Maboko L, Maganga L, Geis S, McCutchan FE, Kijak GH, Kim JH, Arroyo MA, Gerhardt M, Tovanabutra S, Robb ML, Williamson C, Michael NL, Hoelscher M. Viral and host factors associated with the HIV-1 viral load setpoint in adults from Mbeya Region, Tanzania. J Acquir Immune Defic Syndr. 2010 Jul 1; 54(3): 324-30.

Peachman, K, Wieczorek, L, Matyas, G, Polonis, V, Alving, C, Rao, M. The Importance of Antibody Isotype in HIV-1 Virus Capture Assay and in TZM-bl Neutralization. Viral Immunology. 2010 Dec;23(6):627-32.

Michael NL. Oral Preexposure Prophylaxis for HIV - Another Arrow in the Quiver? N Engl J Med. 2010 Nov 23.

Boivin MJ, Ruel TD, Boal HE, Bangirana P, Cao H, Eller LA, Charlebois E, Havlir DV, Kamya MR, Achan J, Akello C, Wong JK. HIV-subtype A is associated with poorer neuropsychological performance compared with subtype D in antiretroviral therapy-naive Ugandan children. AIDS. 2010 May 15;24(8):1163-70. PubMed PMID: 20425886.

Kibuuka H, Kimutai R, Maboko L, Sawe F, Schunk MS, Kroidl A, Shaffer D, Eller LA, Kibaya R, Eller MA, Schindler KB, Schuetz A, Millard M, Kroll J, Dally L, Hoelscher M, Bailer R, Cox JH, Marovich M, Birx DL, Graham BS, Michael NL, de Souza MS, Robb ML. A phase 1/2 study of a multiclade HIV-1 DNA plasmid prime and recombinant adenovirus serotype 5 boost vaccine in HIV-Uninfected East Africans (RV172). J Infect Dis. 2010 Feb 15;201(4):600-7. PubMed PMID: 20078213.

Kiwanuka N, Robb M, Laeyendecker O, Kigozi G, Wabwire-Mangen F, Makumbi FE, Nalugoda F, Kagaayi J, Eller M, Eller LA, Serwadda D, Sewankambo NK, Reynolds SJ, Quinn TC, Gray RH, Wawer MJ, Whalen CC. HIV-1 Viral Subtype Differences in the Rate of CD4+ T-Cell Decline Among HIV Seroincident Antiretroviral Naive Persons in Rakai District, Uganda. J Acquir Immune Defic Syndr. [Epub ahead of print] PubMed PMID: 20010433.

Fox MP, McCoy K, Larson BA, Rosen S, Bii M, Sigei C, Shaffer D, Sawe F, Wasunna M, Simon JL. Improvements in physical wellbeing over the first two years on antiretroviral therapy in western Kenya. AIDS Care. 2010 Feb;22(2):137-45. PubMed PMID: 20390492.

Pelak K, Goldstein DB, Walley NM, Fellay J, Ge D, Shianna KV, Gumbs C, Gao X, Maia JM, Cronin KD, Hussain SK, Carrington M, Michael NL, Weintrob AC; Infectious Disease Clinical Research Program HIV Working Group; National Institute of Allergy and Infectious Diseases Center for HIV/AIDS Vaccine Immunology (CHAVI). Host determinants of HIV-1 control in African Americans. J Infect Dis. 2010 Apr15;201(8):1141-9. Pub Med PMID: 20205591

Ganesan A, Chattopadhyay PK, Brodie TM, Qin J, Gu W, Mascola JR, Michael NL, Follmann DA, Roederer M; Infectious Disease Clinical Research Program HIV Working Group. Immunologic and virologic events in early HIV infection predict subsequent rate of progression. J Infect Dis. 2010 Jan 15;201(2):272-84. PubMed PMID: 20001854.

Kiwanuka N, Robb M, Laeyendecker O, Kigozi G, Wabwire-Mangen F, Makumbi FE, Nalugoda F, Kagaayi J, Eller M, Eller LA, Serwadda D, Sewankambo NK, Reynolds SJ, Quinn TC, Gray RH, Wawer MJ, Whalen CC. HIV-1 viral subtype differences in therate of CD4+ T-cell decline among HIV seroincident antiretroviral naive personsin Rakai district, Uganda.  J Acquir  Immune Defic Syndr. 2010 Jun;54(2):180-4.

Marconi VC, Grandits GA, Weintrob AC, Chun H, Landrum ML, Ganesan A,  Okulicz  JF, Crum-Cianflone N, O'Connell RJ, Lifson A, Wortmann GW, Agan BK, Idcrp TI. Outcomes of highly active antiretroviral therapy in the context of universal access to healthcare: the U.S. Military HIV Natural History Study. AIDS Res Ther. 2010 May 27;7(1):14.

Boivin MJ, Ruel TD, Boal HE, Bangirana P, Cao H, Eller LA, Charlebois E, Havlir DV, Kamya MR, Achan J, Akello C, Wong JK. HIV-subtype A is associated with poorer neuropsychological performance compared with subtype D in antiretroviral therapy-naive Ugandan children. AIDS. 2010 May 15;24(8):1163-70.

Jerome H Kim, Supachai Rerks-Ngarm, Jean-Louis Excler, Nelson L Michael. HIV vaccines: lessons learned and the way forward. Current Opinion in HIV and AIDS 2010; 5:5, 428-434. Online publication date: 1-Sep-2010.

Reilly, L. U.S. Military HIV Research Program: Successfully Integrating HIV Vaccine Research With Prevention, Care, and Treatment. Military Medicine, n7, p42, Thursday, July 1, 2010.

Aronson NE, Wortmann GW, Byrne WR, Howard RS, Bernstein WB, Marovich MA, Polhemus ME, Yoon IK, Hummer  KA, Gasser RA Jr, Oster CN, Benson PM. A randomized controlled trial of local heat therapy versus intravenous sodium Stibogluconate for the treatment of cutaneous Leishmania major infection. PLoS Negl Trop Dis. 2010 Mar 9; 4(3):e628.

Hakre S, Peel SA, O'Connell RJ, Sanders-Buell EE, Jagodzinski LL, Eggleston JC, Myles O, Waterman PE, McBride RH, Eader SA, Davis KW, Rentas FJ, Sateren WB,  Naito NA, Tobler SK, Tovanabutra S, Petruccelli BP, McCutchan FE, Michael NL, Cersovsky SB, Scott PT. Transfusion-transmissible viral infections among US  military recipients of whole blood and platelets during Operation Enduring Freedom and Operation Iraqi Freedom. Transfusion. 2010  Oct 7. doi: 10.1111/j.1537-2995.2010.02906.x. [Epub ahead of print]

Tovanabutra S, Sanders EJ, Graham SM, Mwangome M, Peshu N, McClelland RS, Muhaari A, Crossler J, Price MA, Gilmour J, Michael NL, McCutchan FM. Evaluation of HIV type 1 strains in men having sex with men and in female sex workers in Mombasa, Kenya. AIDS Res Hum Retroviruses. 2010 Feb;26(2):123-31. PubMed PMID: 20156095.

Arroyo MA, Phanuphak N, Krasaesub S, Sirivichayakul S, Assawadarachai V, Poltavee K, Pankam T, Ananworanich J, Paris R, Tovanabutra S, Kijak GH, McCutchan FE, Phanuphak P, Kim JH, de Souza M. HIV type 1 molecular epidemiology among high-risk clients attending the Thai Red Cross Anonymous Clinic in Bangkok, Thailand. AIDS Res Hum Retroviruses. 2010 Jan;26(1):5-12. PubMed PMID: 20055593.

Bautista CT, Todd CS, Abed AM, Botros BA, Strathdee SA, Earhart KC, Safi N, Scott PT. Effects of duration of injection drug use and age at first injection on HCV among IDU in Kabul, Afghanistan. J Public Health (Oxf). 2010 Apr 26. [Epub ahead of print] PubMed PMID: 20421237.

Shaffer DN, Ngetich IK, Bautista CT, Sawe FK, Renzullo PO, Scott PT, Kibaya RM, Imbuki KO, Michael NL, Birx DL, Wasunna MK, Robb ML. HIV-1 incidence rates and risk factors in agricultural workers and dependents in rural Kenya: 36-month follow-up of the Kericho HIV cohort study. J Acquir Immune Defic Syndr. 2010 Apr 1;53(4):514-21. PubMed PMID: 19855286.

Seaman MS, Janes H, Hawkins N, Grandpre LE, Devoy C, Giri A, Coffey RT, Harris

L, Wood B, Daniels MG, Bhattacharya T, Lapedes A, Polonis VR, McCutchan FE,

Gilbert PB, Self SG, Korber BT, Montefiori DC, Mascola JR. Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of  neutralizing  antibodies. J Virol. 2010 Feb;84(3):1439-52. 

Sanders-Buell E, Bose M, Nasir A, Todd CS, Stanekzai MR, Tovanabutra S, Scott PT, Strathdee SA, Tjaden J, Michael NL, McCutchan FE. Distinct Circulating Recombinant HIV-1 Strains Among Injecting Drug Users and Sex Workers in Afghanistan. AIDS Res Hum Retroviruses. 201 May;26(5)605-8.

Singer DE, Bautista CT, O'Connell RJ, Sanders-Buell E, Agan BK, Kijak GH, Hakre S, Sanchez JL, Sateren WB, McCutchan FE, Michael NL, Scott PT. HIV Infection Among U.S. Army and Air Force Military Personnel: Sociodemographic and Genotyping Analysis. AIDS Res Hum Retroviruses.  2010 Aug 1. [Epub ahead of print]

Todd CS, Nasir A, Stanekzai MR, Bautista CT, Botros BA, Scott PT, Strathdee SA, Tjaden J. HIV, hepatitis B, and hepatitis C prevalence and associated risk behaviors among female sex workers in Afghan cities. AIDS. 2010 Jul; 24 Suppl 2:S69-75.

Todd CS, Nasir A, Raza Stanekzai M, Abed AM, Strathdee SA, Bautista CT, Scott  PT, Botros  BA, Tjaden J. Prevalence and Correlates of Syphilis and Condom Use Among Male Injection Drug Users in Four Afghan Cities. Sex Transm Dis. 2010 Jun25. [ Epub ahead of print]