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GHP Research

The Office of the US Global AIDS Coordinator (OGAC) has outlined a plan of investment in innovation and operations research. The goal is to evaluate impact, improve service delivery, and maximize outcomes with our PEPFAR partners in country. MHRP’s collaboration between research and PEPFAR programs provides an excellent platform from which to implement operational research and public heath evaluations. 

African Cohort Study (AFRICOS)

In 2013, MHRP initiated a large, long-term cohort study at multiple African sites that will evaluate HIV prevention, care and treatment services it supports through local facilities, funded by the US President’s Emergency Plan for AIDS Relief (PEPFAR). Named the African Cohort Study (AFRICOS), the study—the first of its kind in sub-Saharan Africa—is taking place at sites in Kenya, Nigeria, Tanzania, and Uganda. Find more information on AFRICOS in the research section.

Public Health Evaluations (PHEs): 

A hypothesis-driven model of research, PHEs compare one program model, approach, or intervention, to another and evaluate based on expected outputs, outcomes, or impacts of the program. 

MHRP’s Kenya program began its first PHE in 2010, called the “Clic-based ART Diagnostic Evaluation Study,” or CLADE. It is an unblinded, randomized prospective, observational, cohort public health evaluation aimed at determining the superiority and cost-effectiveness of two recommended Ministry of Health ART diagnostic evaluation approaches: routine care and viral load guided care. CLADE is unique in that it addresses critical monitoring questions at the actual clinic level and includes actual costs for cost-effectiveness evaluations as a primary study objective. 

Implementation Science

MHRPs Global Health Programs is expanding its implementation science program, which aims to identify novel ways to implement health systems. Several studies will begin in 2015 including one focused on Fisher-folk in Uganda, a peer-to-peer program for PMTCT, and the roll-out of a new electronic patient follow up system in Kenya and Tanzania.

Basic Program Evaluations (BPEs)

MHRP conducts several of these studies that focus on operational research to inform program quality and provide mid-course corrections and improvements for a project. The research identifies promising models or best practices for expansion within the program, and indicates whether a specific program model accomplishes its goals.  

For more information on US-based research, please visit our Research section.