MHRP

Research Contributions

RV144 Vaccine Trial

Thai Study First to Show Some Effectiveness in Preventing HIV

An Army-sponsored phase III clinical trial (RV144) involving more than 16,000 adult volunteers in Thailand showed that an investigational HIV vaccine regimen was safe and modestly effective in preventing HIV infection.

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  • Identified heterosexual transmission of HIV-1
  • Characterized more than half of the known HIV genetic subtypes
  • Successfully integrated care and treatment with basic and clinical vaccine research
  • Led in the development of HIV vaccines for global deployment (non-B subtype)
  • Provided key insights into host genetics and immunopathogenesis
  • Developed MVA HIV vaccine candidate
  • Invented Transcutaneous Immunization (TCI) as a method of adjuvanted immunization by skin patch
  • Helped ensure safe blood supply for warfighter
  • Developed the initial HIV disease staging system

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News & Updates

MHRP International Network

Nigeria, Kenya, Tanzania, Uganda,
Thailand, U.S., Mozambique

Voices from the Field

Voices from the Field

MHRP Profiles

Meet Dr. Milton Omondi, Program Director of the Walter Reed Project (WRP) HIV/AIDS Program, Kisumu West (Kenya). “I feel inspired by the positive impact that the program has had in Kisumu West District,” noted Omondi when asked what he enjoys most about his job.

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In the Spotlight

Jerome Kim, M.D.

Principal Deputy, MHRP and COL, MC, U.S. Army

After two years of extensive laboratory studies following the landmark RV144 trial, investigators from the Army, led by COL Kim, and Duke University have found new clues about the immune responses that may play a role in protection from HIV. In this video, COL Kim discusses the results, which are published in the New England Journal of Medicine.

HIV Diagnostics & Reference Laboratory

MHRP oversees all HIV testing for the Army and serves as the Tri-Service Reference Laboratory.

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Meet our Partners