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March 26, 2014
TB and HIV: A Deadly Combinaton

“Tuberculosis is a major HIV co-infection that, frankly kills many of our patients,” says Maj. Julie Ake, M.D., Associate Director for Vaccine Research and African Cohort Study Protocol Chair. “The TB and HIV epidemics together are really a perfect storm for causing morbidity and mortality in individuals who are affected by HIV. Historically, limitations in TB diagnostics have been challenging...

March 19, 2014
New Studies Enhance Knowledge of Antibodies in HIV Vaccine Trials

Two studies in the March 19 issue of Science Translational Medicine shed new light on the antibodies that appear to have played a role in decreasing the risk of HIV infection in the RV144 HIV vaccine trial. The results provide a better understanding of the immune response a vaccine may need to elicit in order to provide protection from HIV.

In a previous analysis of RV144 results,...

February 26, 2014
MHRP at CROI 2014

MHRP and collaborators gave the following presentations at the annual Conference on Retroviruses and Opportunistic Infections (CROI) that took place March 3–6 in Boston: 

Tuesday, March 4 Loss of HIV Serological Markers Following Early Treatment of Acute HIV Infection  –Mark Manak (MHRP) Poster 395, Session P-F3, 2:30 pm, Exhibit Hall A

Etravirine/Rilpivirine-Specific Mutations...

February 21, 2014
A Focus on Acute Infection Studies

The study of acute HIV infection is critical to the design and development of HIV vaccines and strategies to achieve an undetectable level of virus without antiretrovirals, or a functional cure. By diagnosing HIV within weeks or even days of infection, scientists are afforded the opportunity to study the early events following infection. This provides the opportunity to look at what the virus...

February 18, 2014
MHRP Diagnostics: A Unique Capability within the DoD

MHRP’s Department of Laboratory Diagnostics and Monitoring (DLDM) conducts state-of-the-art HIV and HIV-related infections diagnostics and cutting-edge diagnostic research. The diagnostics program boasts unique capabilities that aren’t replicated within the Department of Defense (DoD). The following is a Q&A with MHRP Diagnostics Chief, Sheila Peel, MSPH, Ph.D.

What is DLDM’s...

February 5, 2014
New study shows that antibodies seen in RV144 may also correlate with lower risk of infection from multiple HIV subtypes

In a study published in PloS One February 4, researchers show that vaccine-induced antibodies targeted at a particular region of the HIV virus, V1V2, correlate with reduced risk of infection but also react not just with the HIV subtype that was most commonly seen in RV144 (the Thai trial), but also with multiple HIV subtypes that circulate in other parts of the world.

This research was...

February 4, 2014
MHRP Welcomes Dr. Jintanat Ananworanich as Associate Director for Therapeutics Research

MHRP is pleased to announce that Dr. Jintanat Ananworanich has joined MHRP in a newly created position, as Associate Director for Therapeutics Research and member of MHRP’s leadership team.

Dr. Ananworanich will oversee adult HIV therapeutic trials as part of the newly-funded MHRP Clinical Trials Unit under the AIDS Clinical Trials Group (ACTG). She will play a critical role in the...

January 10, 2014
Former MHRP Leader Selected as Next U.S. Global AIDS Coordinator

The White House has nominated Dr. Deborah Birx to be the new U.S. Global AIDS Coordinator succeeding Dr. Eric Goosby who left the position in November. Reporting to the Secretary of State, Dr. Birx will coordinate and oversee the U.S. global response to HIV/AIDS, specifically the programs of the U.S. President's Emergency Plan for AIDS Relief (PEPFAR). Prior to this nomination, Dr. Birx...

December 18, 2013
MHRP Named a Clinical Trials Unit for NIH HIV/AIDS Clinical Trials Networks

Seven-year award will advance HIV vaccine and therapeutics research at four MHRP sites in Africa

The U.S. Military HIV Research Program, based at the Walter Reed Army Institute of Research, has been selected as a Clinical Trials Unit (CTU) with four clinical research sites that will receive funding from the National Institute of Allergy and Infectious Diseases (NIAID) to continue HIV...

December 6, 2013
World AIDS Day 2013

Thailand

The Thailand ECHO clinic team represented AFRIMS Retrovirology in Pattaya's annual World AIDS Day parade, an event organized by the Pattaya city council. Pattaya is the hometown of the Thailand ECHO clinic and a Thai resort/vacation destination with a large population of MSM and transgender women working in the tourist and service industries with an ongoing high incidence of...

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