MHRP is a broad-based, highly collaborative, and highly integrated research program with strong epidemiology, preclinical and clinical research capabilities.
Since its inception in 1986, MHRP has developed five sites in Africa and Asia and its research has expanded in scope and diversity.
MHRP is a broad-based, highly collaborative, and highly integrated research program with strong epidemiology, preclinical and clinical research capabilities.
Since its inception in 1986, MHRP has developed five sites in Africa and Asia and its research has expanded in scope and diversity. This growth has been accomplished through the combination of strong vaccine science, careful development of research sites, and partnerships with key research institutions in the U.S. and host countries. Our research portfolio includes:
Our strong preclinical research program is heavily based on humoral and cellular immune assessment laboratories, host genetics, viral genetics and HIV molecular epidemiology, and adjuvant and antigen research.
Clinical studies conducted in the U.S., Africa and Asia play a key role in informing our vaccine development efforts. Our state-of-the-art diagnostics program supports HIV vaccine initiatives by evaluating, optimizing and deploying screening/diagnostic algorithms for accurate and early detection of HIV infection in HIV vaccine trial participants. Our epidemiology and immunology groups continue to play a key role in evaluating candidate vaccine during clinical studies and once the trials have concluded.
MHRP is actively engaged in therapeutic studies to ensure optimal HIV care and treatment services are provided. The AIDS Clinical Trials Group (ACTG) selected MHRP as a Clinical Trials Unit (CTU), with two Clinical Research Sites in Kericho and Eldoret, Kenya. A key area MHRP is currently exploring with the ACTG is HIV-malaria co-infection. MHRP also participates in HIV-TB research and is initiating several PEPFAR-funded therapeutic studies in Africa.
MHRP works closely with other agencies and DoD research programs on collaborative studies in areas such as global emerging infections, malaria diagnostics and co-infections with HIV, Ebola and Marburg DNA plasmid vaccines, and TB/HIV co-diagnosis. These programs help leverage resources and strengthen local research capacity and infrastructures.
MHRP has developed comprehensive HIV prevention, care and treatment programs in Kenya, Uganda, Tanzania and Nigeria, which are supported by the President's Emergency Plan for AIDS Relief (PEPFAR). Our program’s philosophy is firmly anchored on the premise that HIV prevention, care and treatment must be available to all potential research volunteers and their families in order to execute an ethical, sustainable and non-coercive HIV vaccine research program in resource-limited environments.
Our dedicated researchers and support staff are working to stop the spread of HIV/AIDS around the world.
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MHRP is part of the Walter Reed Army Institute of Research
©2013 U.S. Military HIV Research Program
