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MHRP is a broad-based, highly collaborative, and highly integrated research program with strong epidemiology, preclinical and clinical research capabilities.
MHRP defines the HIV epidemic in terms of military impact and is an important partner in international efforts to combat this devastating disease.
MHRP threat assessment and global epidemiology activities are aimed at tracking the HIV epidemic in active duty forces and assessing the risk of HIV and HIV-related infections to U.S. and allied forces deployed overseas.
In addition to Africa and Thailand, MHRP assesses the HIV threat to U.S. military forces in the former Soviet Union and in Eastern Europe/Central Asia, South America and the Caribbean.
By defining the HIV threat to the U.S. Military, MHRP helps inform targeted prevention and also helps defines the requirements for an effective vaccine. In contrast to the U.S. civilian population, which has exposure to a relatively low prevalence of HIV, the U.S. Military, through travel and deployment, can potentially be exposed to high prevalence populations and the whole range of HIV diversity in the global epidemic.
Characterization of threat includes HIV studies in regions of the world where the global epidemic has not yet been adequately defined, with emphasis on areas of potential or actual U.S. Military personnel deployment. In addition, a comprehensive description of HIV-1 infections in U.S. Military personnel, including those plausibly associated with deployment will be crucial for defining requirements for vaccines and prevention. Our program recently defined the peri-deployment time period, the geographic location, and the mode of transmission and fully characterized the molecular epidemiology of all incident HIV infections acquired among Army soldiers deployed to Iraq and Afghanistan during 2001-2007.