Thursday, February 16
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| Time (EST) | Session | Topic | Presenter |
|---|---|---|---|
|
9:00–9:10 |
Opening | Welcome | COL Chad Koenig, WRAIR |
|
9:10–10:40 Moderator:
|
Clinical |
RV254 Acute Infection Study Update | Carlo Sacdalan, IHRI |
| Ongoing / Planned Trials and Science Overview | Sandhya Vasan, MHRP | ||
| Multinational Observational Cohort of HIV and Other Infections (MOCHI) | Josphat Kosgei, HJFMRI Kericho | ||
| Highlighted findings from the Decision Making Study | Gail Henderson, UNC | ||
| RV398: VRC01 administered during Acute HIV Infection | COL Julie Ake, MHRP | ||
| 10:40–11:00 | Break | ||
|
11:00-11:55 Moderator:
|
Neurology and Tissues
|
Recent Findings from the International HIV Neuro Cure Consortium (INHCC) | Serena Spudich, Yale |
| RNAseq on Fresh Tissues | Michael Corley, Weill Cornell | ||
| Tissue Resident Memory in Acute HIV Infection | Alexandra Schuetz, AFRIMS | ||
|
11:55-1:00 Moderator: |
Immunity and Latency |
HLA associations with HIV progression and reservoir | Rasmi Thomas, MHRP |
| Early ART treatment prevents B cell loss and dysfunction in people living with HIV | Samantha Townsley, MHRP | ||
| Role of Innate Immunity During Acute HIV Infection in the Development of Neutralization Breadth | MAJ Gina Griffith, MHRP | ||
| 1:00–1:45 | Lunch | ||
|
1:45–3:00 Moderator: |
HIV Reservoir
|
HIV/SIV latency regulation by AP-1/c-Fos | Diane Bolton, MHRP |
| The first productive and latent HIV infections originate in vivo by infection of resting CD4+ T cells in lymphoid tissues | Ashley Haase, UMN | ||
| HIV specific T cells and reservoir size | Lydie Trautmann, MHRP | ||
| TLR agonist and SIV ENV specific Rhesus mAbs impact on viral rebound | Hannah King, MHRP | ||
| 3:00–3:15 | Break | ||
|
3:15–4:00 Moderator:
|
Closing |
||
| PANEL DISCUSSION ON FUTURE DIRECTIONS |
|
||
| Closing Remarks |
Karl Salzwedel, DAIDS |
||
During the MHRP Acute HIV Science Meeting, unpublished data may be presented and must be treated as confidential. Permission from presenting author(s) must be obtained before communicating results or relevant discussion to outside parties.