The Cellular Immunology Laboratory in Thailand, run by Dr. Alexandra Schuetz, works to understanding the mechanisms by which HIV infection causes dysfunction of the gastrointestinal and reproductive tract, and the lymphoid immune systems. One of the main objectives of her work is to better understand the mucosal determinants of HIV transmission and events occurring during early acute HIV infection and their implication for the development of potential vaccine and cure strategies. In parallel, the Schuetz Lab is conducting research characterizing mucosal, lymphoid and peripheral immune responses in the context of the RV144 follow up studies and other novel vaccine strategies to determine potential mechanisms of protection and to help developing future HIV vaccine candidates.