Janssen
MHRP Collaborator
Hans (JPM) Langedijk currently holds the position of Scientific Director of the Subunit Vaccine Design team, part of Viral Vaccines department at Janssen Vaccines and Prevention. He has set up a protein chemistry group and is responsible for the design and development of novel protein vaccine components against HIV, RSV, Influenza, Corona and other viral targets. For both HIV and RSV he has delivered successful vaccine designs and supported development of both vaccines that are now in clinical trials.
Hans is a biochemist by training and received his PhD in 1993 at the University of Amsterdam. From 2002-2010 he worked at Pepscan Therapeutics as project leader MAb development and external projects mostly relating to miniprotein design. He was principal investigator on grants from several European Union framework programs and the Bill & Melinda Gates foundation in which he was involved in epitope mapping and HIV antigen design. Before joining Pepscan he worked at the Institute of Animal Science and Health (Lelystad, 1993-2002) on structure – function relationships of viral surface proteins. In 1997-1998 he worked as a visiting scientist in the structural virology department of J. Johnson at The Scripps Research Institute in La Jolla, USA. He (co)-authored more than 90 peer reviewed scientific articles, many patent applications and joined thesis committees.
Past and present research activities have focused on integration of combinatorial chemistry, bioinformatics, protein engineering and structure-function relation-based protein research on retroviruses, paramyxoviruses, respiroviruses, pestiviruses, amyloids, neuron – chip interaction, transport peptides and oncology.
Honors
1997 Recepient of ID-Lelystad prize for best researcher
1998 Recepient of Van Bekkum prize for best scientific papers at ID-DLO
2015 The Philip B Hofmann Research Scientist Award
2018 Janssen Fellow