Biography
Dr. Crowell is Senior Director of HJF Global Infectious Diseases and Director of the HJF component of MHRP, helping to coordinate all basic, translational, and clinical research activities of the program.
Dr. Crowell is a physician specialist in infectious diseases who received his M.D. from the University of Southern California Keck School of Medicine and his Ph.D. in clinical investigation from the Johns Hopkins Bloomberg School of Public Health. He completed his residency in internal medicine and international health at University Hospitals Case Medical Center and his fellowship in infectious diseases at the Johns Hopkins University School of Medicine.
Dr. Crowell is a Professor in the Division of Infectious Diseases at the Uniformed Services University and has an adjunct appointment at Johns Hopkins University, where he provides inpatient consultative clinical care. He is a Deputy Editor for the Journal of the International AIDS Society and serves on the editorial boards of AIDS and AIDS Research and Therapy. He is an active investigator with the NIH-sponsored AIDS Clinical Trials Group (ACTG), having served as an elected member of the HIV Reservoirs and Viral Eradication (Cure) Transformative Science Group and on the leadership teams for multinational studies of acute HIV and the use of broadly-neutralizing antibodies for HIV therapy. He is a past recipient of the ACTG John Carey Young Investigator Award.
Dr. Crowell has published extensively on clinical outcomes among people living with or at risk for HIV, with a focus on U.S. military service members, marginalized and stigmatized populations, elite controllers, and individuals diagnosed and treated during acute HIV. He has overseen several multinational clinical trials of novel interventions to achieve HIV remission and has contributed to the evaluation of preventive vaccine candidates for HIV and other infectious diseases.
Selected Publications
Crowell TA, Hsieh HC, Wang X, Chi X, Gayle B, Berjohn CM, Blaylock JM, Yabes JM, Larson DT, Powers JH, O’Connell RJ, Ganesan A, Agan BK for the Infectious Disease Clinical Research Program (IDCRP) HIV Working Group. “Antiretroviral Therapy within Two Years of HIV Acquisition is Associated with Fewer Viral Blips: A Retrospective Analysis of Over 20 Years of Data from the U.S. Military HIV Natural History Study.” Clin Infect Dis. 2025 Oct 6;81(3):499-509. doi: 10.1093/cid/ciaf103. PMID: 40059621. PMCID: PMC12497960.
Schluck G, Romo ML, Kosgei J, Thigpen MC, Burns N, Bor R, Langat D, Akoth C, Yates A, Charles C, Qian H, Gayle B, Yacovone M, Sawe F, Crowell TA for the Multinational Observational Cohort of HIV and other Infections (MOCHI) Study Group. “Limited awareness and use of HIV post-exposure prophylaxis among people vulnerable to HIV acquisition in Western Kenya: A cross-sectional analysis.” J Int AIDS Soc. 2025 Jun:28 Suppl 1:e26472. doi: 10.1002/jia2.26472. PMID: 40569897. PMCID: PMC12231640.
Romo ML, Schluck G, Kosgei J, Akoth C, Bor R, Langat D, Charles C, Adjei P, Gayle B, LeeVan E, Chang D, Yates A, Yacovone M, Ake JA, Sawe F, Crowell TA for the Multinational Observational Cohort of HIV and other Infections (MOCHI) Study Group. “Pre-exposure prophylaxis implementation gaps among people vulnerable to HIV acquisition: a cross-sectional analysis in two communities in western Kenya, 2021-2023.” J Int AIDS Soc. 2024 Nov;27(11):e26372. doi: 10.1002/jia2.26372. PMID: 39496511. PMCID: PMC11534481.
Crowell TA, Ritz J, Zheng L, Naqvi A, Cyktor JC, Puleo J, Clagett B, Lama JR, Kanyama C, Little SJ, Cohn SE, Riddler SA, Collier AC, Heath SL, Tantivitayakul P, Grinsztejn B, Arduino RC, Rooney JF, van Zyl GU, Coombs RW, Fox L, Ananworanich J, Eron JJ, Sieg SF, Mellors JW, Daar ES for the AIDS Clinical Trials Group (ACTG) A5354/EARLIER Study Team. “Impact of antiretroviral therapy during acute or early HIV infection on virologic and immunologic outcomes: results from a single-arm, open-label, multinational clinical trial.” AIDS. 2024 Jul 1;38(8):1141-1152. doi: 10.1097/QAD.0000000000003881. PMID: 38489580. PMCID: PMC11323228.
Esber A, Dear N, King D, Francisco L, Sing’oei V, Owuoth J, Maswai J, Iroezindu M, Bahemana E, Kibuuka H, Shah N, Polyak CS, Ake JA, Crowell TA on behalf of the AFRICOS Study Group. “Achieving the 3rd 95 in sub-Saharan Africa: application of machine learning approaches to predict viral failure.” AIDS. 2023 Oct 1;37(12):1861-1870. doi: 10.1097/QAD.0000000000003646. PMID: 37418549.
Crowell TA, Danboise B, Parikh AP, Esber AL, Dear N, Coakley P, Kasembeli A, Maswai J, Khamadi SA, Bahemana E, Iroezindu M, Kiweewa F, Owuoth J, Freeman J, Jagodzinski LL, Malia JA, Eller LA, Tovanabutra S, Peel SA, Ake JA, Polyak CS for the AFRICOS Study Group. “Pre-Treatment and Acquired Antiretroviral Drug Resistance among Persons Living with HIV in Four African Countries.” Clin Infect Dis. 2021 Oct 5;73(7):e2311-e2322. doi: 10.1093/cid/ciaa1161. PMID: 32785695. PMCID: PMC8492117.
Crowell TA, Ritz J, Coombs RW, Zheng L, Eron JJ, Mellors JW, Dragavon J, van Zyl GU, Lama JR, Ruxrungtham K, Grinsztejn B, Arduino RC, Fox L, Ananworanich J, Daar ES for the AIDS Clinical Trials Group (ACTG) A5354/EARLIER (Early ART to Limit Infection and Establishment of Reservoir) Study Team. “Novel Criteria for Diagnosing Acute and Early Human Immunodeficiency Virus Infection in a Multinational Study of Early Antiretroviral Therapy Initiation.” Clin Infect Dis. 2021 Aug 2;73(3):e643-e651. doi: 10.1093/cid/ciaa1893. PMID: 33382405. PMCID: PMC8326583.
Crowell TA, Pinyakorn S, Sacdalan C, Kroon E, Colby DJ, Puttamaswin S, Ubolyam S, Trichavaroj R, Butterworth O, Turk E, McCullough C, Chomont N, de Souza M, Robb ML, Phanuphak N, Ananworanich J for the RV254/SEARCH010 Study Group. “Viral Blips After Treatment Initiation During Acute Human Immunodeficiency Virus Infection.” Clin Infect Dis. 2020 Jun 10;70(12):2706-2709. doi: 10.1093/cid/ciz936. PMID: 31550044. PMCID: PMC7286371.
Crowell TA, Colby DJ, Pinyakorn S, Sacdalan C, Pagliuzza A, Intasan J, Benjapornpong K, Tangnaree K, Chomchey N, Kroon E, de Souza MS, Tovanabutra S, Rolland M, Eller MA, Paquin-Poulx D, Bolton DL, Tokarev A, Thomas R, Takata H, Trautmann L, Krebs SJ, Modjarrad K, McDermott AB, Bailer RT, Doria-Rose N, Patel B, Gorelick RJ, Fullmer BA, Schuetz A, Grandin PV, O’Connell RJ, Ledgerwood JE, Graham BS, Tressler R, Mascola JR, Chomont N, Michael NL, Robb ML, Phanuphak N, Ananworanich J for the RV397 Study Group. “Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial.” Lancet HIV. 2019 May;6(5):e297-e306. doi: 10.1016/S2352-3018(19)30053-0. PMID: 31000477. PMCID: PMC6693657.
Crowell TA, Colby DJ, Pinyakorn S, Fletcher JLK, Kroon E, Schuetz A, Krebs SJ, Slike BM, Leyre L, Chomont N, Jagodzinski LL, Sereti I, Utay NS, Dewar R, Rerknimitr R, Chomchey N, Trichavaroj R, Valcour VG, Spudich S, Michael NL, Robb ML, Phanuphak N, Ananworanich J for the RV254/SEARCH010 Study Group. “Acute Retroviral Syndrome is Associated with High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments.” Clin Infect Dis. 2018 May 2;66(10):1540-1549. doi: 10.1093/cid/cix1063. PMID: 29228130. PMCID: PMC5930255.
Crowell TA, Keshinro B, Baral SD, Schwartz SR, Nowak RG, Adebajo S, Blattner WA, Charurat ME, Ake J for the TRUST/RV368 Study Group. “Stigma, access to healthcare, and HIV risks among men who sell sex to men in Nigeria.” J Int AIDS Soc. 2017 Apr 20;20(1):21489. doi: 10.7448/IAS.20.01.21489. PMID: 28453241. PMCID: PMC5515015.
Crowell TA, Fletcher JLK, Sereti I, Pinyakorn S, Dewar R, Krebs SJ, Chomchey N, Rerknimitr R, Schuetz A, Michael NL, Phanuphak N, Chomont N, Ananworanich J for the RV254/SEARCH010 Study Group. “Initiation of antiretroviral therapy before detection of colonic infiltration by HIV reduces viral reservoirs, inflammation and immune activation.” J Int AIDS Soc. 2016 Sep 15;19(1):21163. doi: 10.7448/IAS.19.1.21163. PMID: 27637172. PMCID: PMC5026729.
Crowell TA, Ganesan A, Berry SA, Deiss RG, Agan BK, Okulicz JF for the Infectious Disease Clinical Research Program (IDCRP) HIV Working Group. “Hospitalizations among HIV controllers and persons with medically controlled HIV in the U.S. Military HIV Natural History Study.” J Int AIDS Soc. 2016 Mar 7;19(1):20524. doi: 10.7448/IAS.19.1.20524. PMID: 26955965. PMCID: PMC4783305.
Crowell TA, Gebo KA, Blankson JN, Korthuis PT, Yehia BR, Rutstein RM, Moore RD, Sharp V, Nijhawan AE, Mathews WC, Hanau LH, Corales RB, Beil R, Somboonwit C, Edelstein H, Allen SL, Berry SA for the HIV Research Network. “Hospitalization Rates and Reasons among HIV Elite Controllers and Persons with Medically Controlled HIV Infection.” J Infect Dis. 2015 Jun 1;211(11):1692-702. doi: 10.1093/infdis/jiu809. PMID: 25512624. PMCID: PMC4447832
Full list of publications: https://www.ncbi.nlm.nih.gov/myncbi/12Y18Phwn4hkO/bibliography/public