Langat A, Callahan TL, Yonga I, Ochanda B, Waruru A, Ng'anga LW, Katana A, Onyango B, Singa B, Oyule S, Githuka G, Omoto L, Muli J, Tylleskar T, Modi S. Associations of Sociodemographic and Clinical Factors with Late Presentation for Early Infant HIV Diagnosis (EID) Services in Kenya. Int J MCH AIDS. 2021;10(2):210-220. doi: 10.21106/ijma.537. Epub 2021 Dec 13. PMID: 34938594.
Joyce MG, King HAD, Elakhal-Naouar I, Ahmed A, Peachman KK, Macedo Cincotta C, Subra C, Chen RE, Thomas PV, Chen WH, Sankhala RS, Hajduczki A, Martinez EJ, Peterson CE, Chang WC, Choe M, Smith C, Lee PJ, Headley JA, Taddese MG, Elyard HA, Cook A, Anderson A, Wuertz KM, Dong M, Swafford I, Case JB, Currier JR, Lal KG, Molnar S, Nair MS, Dussupt V, Daye SP, Zeng X, Barkei EK, Staples HM, Alfson K, Carrion R, Krebs SJ, Paquin-Proulx D, Karasavva N, Polonis VR, Jagodzinski LL, Amare MF, Vasan S, Scott PT, Huang Y, Ho DD, de Val N, Diamond MS, Lewis MG, Rao M, Matyas GR, Gromowski GD, Peel SA, Michael NL, Bolton DL, Modjarrad K. A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates. Sci Transl Med. 2021 Dec 16:eabi5735. Online ahead of print. PMID: 34914540.
Carmen JM, Shrivastava S, Lu Z, Anderson A, Morrison EB, Sankhala RS, Chen WH, Chang WC, Bolton JS, Matyas GR, Michael NL, Joyce MG, Modjarrad K, Currier JR, Bergmann-Leitner E, Malloy AMW, Rao M. SARS-CoV-2 ferritin nanoparticle vaccine induces robust innate immune activity driving polyfunctional spike-specific T cell responses. NPJ Vaccines. 2021 Dec 13;6(1):151. doi: 10.1038/s41541-021-00414-4. PMID: 34903722.
Scaria PV, Anderson C, Muratova O, Alani N, Trinh HV, Nadakal ST, Zaidi I, Lambert L, Beck Z, Barnafo EK, Rausch KM, Rowe C, Chen B, Matyas GR, Rao M, Alving CR, Narum DL, Duffy PE. Malaria transmission-blocking conjugate vaccine in ALFQ adjuvant induces durable functional immune responses in rhesus macaques. NPJ Vaccines. 2021 Dec 9;6(1):148. doi: 10.1038/s41541-021-00407-3. PMID: 34887448.
Sharma V, Creegan M, Tokarev A, Hsu D, Slike BM, Sacdalan C, Chan P, Spudich S, Ananworanich J, Eller MA, Krebs SJ, Vasan S, Bolton DL; RV254/SEARCH010 and RV304/SEARCH013 Study Teams. Cerebrospinal fluid CD4+ T cell infection in humans and macaques during acute HIV-1 and SHIV infection. PLoS Pathog. 2021 Dec 7;17(12):e1010105. doi: 10.1371/journal.ppat.1010105. Online ahead of print. PMID: 34874976.
Kibuuka H, Musingye E, Mwesigwa B, Semwogerere M, Iroezindu M, Bahemana E, Maswai J, Owuoth J, Esber A, Dear N, Crowell TA, Polyak CS, Ake JA; AFRICOS Study Group. Predictors of All-Cause Mortality among People with HIV in a Prospective Cohort Study in East Africa and Nigeria. Clin Infect Dis. 2021 Dec 3:ciab995. doi: 10.1093/cid/ciab995. Online ahead of print. PMID: 34864933.
Capitine IPU, Macicame IB, Uanela AM, Bhatt NB, Yates A, Milazzo M, Nwoga C, Crowell TA, Michael NL, Robb ML, Jani IV, Kroidl A, Polyak CS, De Schacht C; RV363 Study Group. Young at risk-people in Maputo City, Mozambique, present a high willingness to participate in HIV trials: Results from an HIV vaccine preparedness cohort study. PLoS One. 2021 Dec 2;16(12):e0260126. doi: 10.1371/journal.pone.0260126. eCollection 2021. PMID: 34855790.
Nowak RG, Bentzen SM, Schumaker LM, Ambulos NP, Ndembi N, Dauda W, Mitchell A, Mathias TJ, Crowell TA, Baral SD, Blattner WA, Charurat ME, Palefsky JM, Cullen KJ; TRUST/RV368 Study Group. Evaluating the Jaccard Similarity Index as a Persistence Measure of Multiple Anal Human Papillomavirus among Nigerian Men Who Have Sex with Men. Sex Transm Dis. 2021 Nov 29. doi: 10.1097/OLQ.0000000000001587. Online ahead of print. PMID: 34840323.
Somi N, Dear N, Reed D, Parikh A, Lwilla A, Bahemana E, Khamadi S, Iroezindu M, Kibuuka H, Maswai J, Crowell TA, Owuoth J, Maganga L, Polyak C, Ake J, Esber A; AFRICOS Study Group. Perceived satisfaction with HIV care and its association with adherence to antiretroviral therapy and viral suppression in the African Cohort Study. AIDS Res Ther. 2021 Nov 25;18(1):89. doi: 10.1186/s12981-021-00414-3. PMID: 34823544.
Kim J, Vasan S, Kim JH, Ake JA. Current approaches to HIV vaccine development: a narrative review. J Int AIDS Soc. 2021 Nov;24 Suppl 7(Suppl 7):e25793. doi: 10.1002/jia2.25793. PMID: 34806296.
Crowell TA, Daud II, Maswai J, Owuoth J, Sing'oei V, Imbach M, Dear N, Sawe F, Eller LA, Polyak CS, Ake JA; AFRICOS Study Group. Severe acute respiratory syndrome coronavirus-2 antibody prevalence in people with and without HIV in rural Western Kenya, January to March 2020. AIDS. 2021 Nov 15;35(14):2401-2404. doi: 10.1097/QAD.0000000000003054. PMID: 34482354.
Mitchell JL, Pollara J, Dietze K, Edwards RW, Nohara J, N'guessan KF, Zemil M, Buranapraditkun S, Takata H, Li Y, Muir R, Kroon E, Pinyakorn S, Jha S, Manasnayakorn S, Chottanapund S, Thantiworasit P, Prueksakaew P, Ratnaratorn N, Nuntapinit B, Fox L, Tovanabutra S, Paquin-Proulx D, Wieczorek L, Polonis VR, Maldarelli F, Haddad EK, Phanuphak P, Sacdalan CP, Rolland M, Phanuphak N, Ananworanich J, Vasan S, Ferrari G, Trautmann L. Anti-HIV antibody development up to one year after antiretroviral therapy initiation in acute HIV infection. J Clin Invest. 2021 Nov 11:e150937. doi: 10.1172/JCI150937. Online ahead of print. PMID: 34762600.
Paquin-Proulx D, Lal KG, Phuang-Ngern Y, Creegan M, Tokarev A, Suhkumvittaya S, Alrubayyi A, Kroon E, Pinyakorn S, Slike BM, Bolton DL, Krebs SJ, Eller LA, Sajjaweerawan C, Pagliuzza A, Chomont N, Rerknimitr R, Chomchey N, Phanuphak N, de Souza MS, Michael NL, Robb ML, Ananworanich J, Sandberg JK, Eller MA, Schuetz A; RV217; RV254/SEARCH010; RV304/SEARCH013; Study Groups. Preferential and persistent impact of acute HIV-1 infection on CD4+ iNKT cells in colonic mucosa. Proc Natl Acad Sci U S A. 2021 Nov 16;118(46):e2104721118. doi: 10.1073/pnas.2104721118. PMID: 34753817.
Saunders KO, Pardi N, Parks R, Santra S, Mu Z, Sutherland L, Scearce R, Barr M, Eaton A, Hernandez G, Goodman D, Hogan MJ, Tombacz I, Gordon DN, Rountree RW, Wang Y, Lewis MG, Pierson TC, Barbosa C, Tam Y, Matyas GR, Rao M, Beck Z, Shen X, Ferrari G, Tomaras GD, Montefiori DC, Weissman D, Haynes BF. Author Correction: Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates. NPJ Vaccines. 2021 Nov 6;6(1):136. doi: 10.1038/s41541-021-00397-2. PMID: 34743171.
Gilbert L, Dear N, Esber A, Iroezindu M, Bahemana E, Kibuuka H, Owuoth J, Maswai J, Crowell TA, Polyak CS, Ake JA; AFRICOS Study Group. Prevalence and risk factors associated with HIV and syphilis co-infection in the African Cohort Study: a cross-sectional study. BMC Infect Dis. 2021 Oct 30;21(1):1123. doi: 10.1186/s12879-021-06668-6. PMID: 34717564.
Dussupt V, Sankhala RS, Mendez-Rivera L, Townsley SM, Schmidt F, Wieczorek L, Lal KG, Donofrio GC, Tran U, Jackson ND, Zaky WI, Zemil M, Tritsch SR, Chen WH, Martinez EJ, Ahmed A, Choe M, Chang WC, Hajduczki A, Jian N, Peterson CE, Rees PA, Rutkowska M, Slike BM, Selverian CN, Swafford I, Teng IT, Thomas PV, Zhou T, Smith CJ, Currier JR, Kwong PD, Rolland M, Davidson E, Doranz BJ, Mores CN, Hatziioannou T, Reiley WW, Bieniasz PD, Paquin-Proulx D, Gromowski GD, Polonis VR, Michael NL, Modjarrad K, Joyce MG, Krebs SJ. Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations. Nat Immunol. 2021 Oct 29. doi: 10.1038/s41590-021-01068-z. Online ahead of print. PMID: 34716452.
Tomalka JA, Pelletier AN, Fourati S, Latif MB, Sharma A, Furr K, Carlson K, Lifton M, Gonzalez A, Wilkinson P, Franchini G, Parks R, Letvin N, Yates N, Seaton K, Tomaras G, Tartaglia J, Robb ML, Michael NL, Koup R, Haynes B, Santra S, Sekaly RP. The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination. Nat Immunol. 2021 Oct;22(10):1294-1305. doi: 10.1038/s41590-021-01026-9. Epub 2021 Sep 23. PMID: 34556879.
Bailey LE, Siberry GK, Agaba P, Douglas M, Clinkscales JR, Godfrey C. The impact of COVID-19 on multi-month dispensing (MMD) policies for antiretroviral therapy (ART) and MMD uptake in 21 PEPFAR-supported countries: a multi-country analysis. J Int AIDS Soc. 2021 Oct;24 Suppl 6(Suppl 6):e25794. doi: 10.1002/jia2.25794. PMID: 34713578.
Wuertz KM, Barkei EK, Chen WH, Martinez EJ, Lakhal-Naouar I, Jagodzinski LL, Paquin-Proulx D, Gromowski GD, Swafford I, Ganesh A, Dong M, Zeng X, Thomas PV, Sankhala RS, Hajduczki A, Peterson CE, Kuklis C, Soman S, Wieczorek L, Zemil M, Anderson A, Darden J, Hernandez H, Grove H, Dussupt V, Hack H, de la Barrera R, Zarling S, Wood JF, Froude JW, Gagne M, Henry AR, Mokhtari EB, Mudvari P, Krebs SJ, Pekosz AS, Currier JR, Kar S, Porto M, Winn A, Radzyminski K, Lewis MG, Vasan S, Suthar M, Polonis VR, Matyas GR, Boritz EA, Douek DC, Seder RA, Daye SP, Rao M, Peel SA, Joyce MG, Bolton DL, Michael NL, Modjarrad K. A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus variant challenge. NPJ Vaccines. 2021 Oct 28;6(1):129. doi: 10.1038/s41541-021-00392-7. PMID: 34711815.
Yu J, Collins ND, Mercado NB, McMahan K, Chandrashekar A, Liu J, Anioke T, Chang A, Giffin VM, Hope DL, Sellers D, Nampanya F, Gardner S, Barrett J, Wan H, Velasco J, Teow E, Cook A, Van Ry A, Pessaint L, Andersen H, Lewis MG, Hofer C, Burke DS, Barkei EK, King HAD, Subra C, Bolton D, Modjarrad K, Michael NL, Barouch DH. Protective Efficacy of Gastrointestinal SARS-CoV-2 Delivery Against Intranasal and Intratracheal SARS-CoV-2 Challenge in Rhesus Macaques. J Virol. 2021 Oct 27:JVI0159921. doi: 10.1128/JVI.01599-21. Online ahead of print. PMID: 34705557.
Shrivastava S, Kottilil S, Sherman KE, Masur H, Tang L. CCR5+ T-Cells Homed to the Liver Exhibit Inflammatory and Profibrogenic Signatures in Chronic HIV/HCV-Coinfected Patients. Viruses. 2021 Oct 14;13(10):2074. doi: 10.3390/v13102074. PMID: 34696504.
Thomas R, Chansinghakul D, Limkittikul K, Gilbert PB, Hattasingh W, Moodie Z, Shangguan S, Frago C, Dulyachai W, Li SS, Jarman RG, Geretz A, Bouckenooghe A, Sabchareon A, Juraska M, Ehrenberg P, Michael NL, Bailleux F, Bryant C, Gurunathan S. Associations of human leukocyte antigen with neutralizing antibody titers in a tetravalent dengue vaccine phase 2 efficacy trial in Thailand. Hum Immunol. 2021 Oct 8:S0198-8859(21)00236-6. doi: 10.1016/j.humimm.2021.09.006. Online ahead of print. PMID: 34635391.
Esber A, Dear N, Reed D, Bahemana E, Owouth J, Maswai J, Kibuuka H, Iroezindu M, Crowell TA, Polyak CS, Akom E, Ake JA; AFRICOS Study Group. Temporal trends in self-reported HIV stigma and association with adherence and viral suppression in the African Cohort Study. AIDS Care. 2021 Oct 6:1-8. doi: 10.1080/09540121.2021.1984380. Online ahead of print. PMID: 34612100.
Oluniyi PE, Ajogbasile FV, Zhou S, Fred-Akintunwa I, Polyak CS, Ake JA, Tovanabutra S, Iroezindu M, Rolland M, Happi CT. HIV-1 drug resistance and genetic diversity in a cohort of people living with HIV-1 in Nigeria. AIDS. 2021 Oct 7. doi: 10.1097/QAD.0000000000003098. Online ahead of print. PMID: 34628443.
Shrivastava S, Kottilil S, Sherman KE, Masur H, Tang L. CCR5+ T-Cells Homed to the Liver Exhibit Inflammatory and Profibrogenic Signatures in Chronic HIV/HCV-Coinfected Patients. Viruses. 2021 Oct 14;13(10):2074. doi: 10.3390/v13102074. PMID: 34696504.
King HAD, Joyce MG, Lakhal-Naouar I, Ahmed A, Cincotta CM, Subra C, Peachman KK, Hack HR, Chen RE, Thomas PV, Chen WH, Sankhala RS, Hajduczki A, Martinez EJ, Peterson CE, Chang WC, Choe M, Smith C, Headley JA, Elyard HA, Cook A, Anderson A, Wuertz KM, Dong M, Swafford I, Case JB, Currier JR, Lal KG, Amare MF, Dussupt V, Molnar S, Daye SP, Zeng X, Barkei EK, Alfson K, Staples HM, Carrion R, Krebs SJ, Paquin-Proulx D, Karasavvas N, Polonis VR, Jagodzinski LL, Vasan S, Scott PT, Huang Y, Nair MS, Ho DD, de Val N, Diamond MS, Lewis MG, Rao M, Matyas GR, Gromowski GD, Peel SA, Michael NL, Modjarrad K, Bolton DL. Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques. Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2106433118. doi: 10.1073/pnas.2106433118. PMID: 34470866.
Shangguan S, Ehrenberg PK, Geretz A, Yum L, Kundu G, May K, Fourati S, Nganou-Makamdop K, Williams LD, Sawant S, Lewitus E, Pitisuttithum P, Nitayaphan S, Chariyalertsak S, Rerks-Ngarm S, Rolland M, Douek DC, Gilbert P, Tomaras GD, Michael NL, Vasan S, Thomas R. Monocyte-derived transcriptome signature indicates antibody-dependent cellular phagocytosis as a potential mechanism of vaccine-induced protection against HIV-1. Elife. 2021 Sep 17;10:e69577. doi: 10.7554/eLife.69577. PMID: 34533134.
Kamau E, Yates A, Maisiba R, Singoei V, Opot B, Adeny R, Arima CO, Otieno V, Sumbi CS, Okoth RO, Abdi F, Mwalo M, Ochola J, Otieno J, Ake J, Imbach M, Turley HA, Juma D, Akala HM, Owuoth J, Andagalu B, Crowell TA, Nwoga C, Cowden J, Polyak CS; RV393 Study Group. Epidemiological and clinical implications of asymptomatic malaria and schistosomiasis co-infections in a rural community in western Kenya. BMC Infect Dis. 2021 Sep 9;21(1):937. doi: 10.1186/s12879-021-06626-2. PMID: 34503469.
Crowell TA, Daud II, Maswai J, Owuoth J, Sing'oei V, Imbach M, Dear N, Sawe F, Eller LA, Polyak CS, Ake JA; AFRICOS Study Group. SARS-CoV-2 antibody prevalence in people with and without HIV in rural western Kenya, January to March 2020. AIDS. 2021 Sep 1. doi: 10.1097/QAD.0000000000003054. Online ahead of print. PMID: 34482354.
Townsley SM, Leggat DJ, Prabhakaran M, McDermott AB, Krebs SJ. Sequential staining of HIV gp140 to capture antigen-specific human B cells via flow cytometry. STAR Protoc. 2021 Aug 24;2(3):100771. doi: 10.1016/j.xpro.2021.100771. eCollection 2021 Sep 17. PMID: 34471908.
Kammers K, Chen A, Monaco DR, Hudelson SE, Grant-McAuley W, Moore RD, Alter G, Deeks SG, Morrison CS, Eller LA, Blankson JN, Laeyendecker O, Ruczinski I, Eshleman SH, Larman HB. HIV Antibody Profiles in HIV Controllers and Persons With Treatment-Induced Viral Suppression. Front Immunol. 2021 Aug 26;12:740395. doi: 10.3389/fimmu.2021.740395. eCollection 2021. PMID: 34512672.
Onyenakie CC, Nnakwe RU, Dear N, Esber A, Bahemana E, Kibuuka H, Maswai J, Owuoth J, Crowell TA, Polyak CS, Ake JA, Iroezindu M; AFRICOS Study Team. Prevalence and Predictors of Food Insecurity among People Living with and without HIV in the African Cohort Study. Public Health Nutr. 2021 Aug 23:1-37. doi: 10.1017/S136898002100361X. Online ahead of print. PMID: 34420547.
Crowell TA, Qian H, Tiemann C, Lehmann C, Boesecke C, Stoehr A, Hartikainen J, Esser S, Bickel M, Spinner CD, Schneeweiß S, Cordes C, Brockmeyer N, Jessen H, Robb ML, Michael NL, Jansen K, Streeck H; BRAHMS Study Team. Factors associated with testing for HIV and hepatitis C among behaviorally vulnerable men in Germany: a cross-sectional analysis upon enrollment into an observational cohort. AIDS Res Ther. 2021 Aug 16;18(1):52. doi: 10.1186/s12981-021-00378-4. PMID: 34399787.
Corley MJ, Sacdalan C, Pang APS, Chomchey N, Ratnaratorn N, Valcour V, Kroon E, Cho KS, Belden AC, Colby D, Robb M, Hsu D, Spudich S, Paul R, Vasan S, Ndhlovu LC; SEARCH010/RV254 and SEARCH013/RV304 study groups. Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ART. PLoS Pathog. 2021 Aug 13;17(8):e1009785. doi: 10.1371/journal.ppat.1009785. eCollection 2021 Aug. PMID: 34388205.
Ajibola O, Diop MF, Ghansah A, Amenga-Etego L, Golassa L, Apinjoh T, Randrianarivelojosia M, Maiga-Ascofare O, Yavo W, Bouyou-Akotet M, Oyebola KM, Andagalu B, D'Alessandro U, Ishengoma D, Djimde AA, Kamau E, Amambua-Ngwa A. In silico characterisation of putative Plasmodium falciparum vaccine candidates in African malaria populations. Sci Rep. 2021 Aug 10;11(1):16215. doi: 10.1038/s41598-021-95442-4. PMID: 34376744.
Li Y, Bai H, Sanders-Buell E, Dussupt V, Townsley S, Donofrio G, Bose M, O'Sullivan AM, Kibuuka H, Maganga L, Nitayaphan S, Kosgei J, Pitisuttithum P, Rerks-Ngarm S, Eller LA, Michael NL, Robb ML, Ake J, Vasan S, Tovanabutra S, Krebs SJ, Rolland M. Limited Evidence for a Relationship between HIV-1 Glycan Shield Features in Early Infection and the Development of Neutralization Breadth. J Virol. 2021 Aug 10;95(17):e0079721. doi: 10.1128/JVI.00797-21. Epub 2021 Aug 10. PMID: 34160251.
Corey L, Beyrer C, Cohen MS, Michael NL, Bedford T, Rolland M. SARS-CoV-2 Variants in Patients with Immunosuppression. N Engl J Med. 2021 Aug 5;385(6):562-566. doi: 10.1056/NEJMsb2104756.PMID: 34347959.
Hsu DC, Mellors JW, Vasan S. Can Broadly Neutralizing HIV-1 Antibodies Help Achieve an ART-Free Remission? Front Immunol. 2021 Jul 12;12:710044. doi: 10.3389/fimmu.2021.710044. eCollection 2021. PMID: 34322136.
MalariaGEN, Ahouidi A, Ali M, Almagro-Garcia J, Amambua-Ngwa A, Amaratunga C, Amato R, Amenga-Etego L, Andagalu B, Anderson TJC, Andrianaranjaka V, Apinjoh T, Ariani C, Ashley EA, Auburn S, Awandare GA, Ba H, Baraka V, Barry AE, Bejon P, Bertin GI, Boni MF, Borrmann S, Bousema T, Branch O, Bull PC, Busby GBJ, Chookajorn T, Chotivanich K, Claessens A, Conway D, Craig A, D'Alessandro U, Dama S, Day NP, Denis B, Diakite M, Djimdé A, Dolecek C, Dondorp AM, Drakeley C, Drury E, Duffy P, Echeverry DF, Egwang TG, Erko B, Fairhurst RM, Faiz A, Fanello CA, Fukuda MM, Gamboa D, Ghansah A, Golassa L, Goncalves S, Hamilton WL, Harrison GLA, Hart L, Henrichs C, Hien TT, Hill CA, Hodgson A, Hubbart C, Imwong M, Ishengoma DS, Jackson SA, Jacob CG, Jeffery B, Jeffreys AE, Johnson KJ, Jyothi D, Kamaliddin C, Kamau E, Kekre M, Kluczynski K, Kochakarn T, Konaté A, Kwiatkowski DP, Kyaw MP, Lim P, Lon C, Loua KM, Maïga-Ascofaré O, Malangone C, Manske M, Marfurt J, Marsh K, Mayxay M, Miles A, Miotto O, Mobegi V, Mokuolu OA, Montgomery J, Mueller I, Newton PN, Nguyen T, Nguyen TN, Noedl H, Nosten F, Noviyanti R, Nzila A, Ochola-Oyier LI, Ocholla H, Oduro A, Omedo I, Onyamboko MA, Ouedraogo JB, Oyebola K, Pearson RD, Peshu N, Phyo AP, Plowe CV, Price RN, Pukrittayakamee S, Randrianarivelojosia M, Rayner JC, Ringwald P, Rockett KA, Rowlands K, Ruiz L, Saunders D, Shayo A, Siba P, Simpson VJ, Stalker J, Su XZ, Sutherland C, Takala-Harrison S, Tavul L, Thathy V, Tshefu A, Verra F, Vinetz J, Wellems TE, Wendler J, White NJ, Wright I, Yavo W, Ye H. An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples. Wellcome Open Res. 2021 Jul 13;6:42. doi: 10.12688/wellcomeopenres.16168.2. eCollection 2021. PMID: 33824913.
Reed DM, Esber AL, Crowell TA, Ganesan K, Kibuuka H, Maswai J, Owuoth J, Bahemana E, Iroezindu M, Ake JA, Polyak CS; AFRICOS Study Team. Persons living with HIV in sero-discordant partnerships experience improved HIV care engagement compared with persons living with HIV in sero-concordant partnerships: a cross-sectional analysis of four African countries. AIDS Res Ther. 2021 Jul 22;18(1):43. doi: 10.1186/s12981-021-00363-x. PMID: 34294086.
Mbah P, Iroezindu M, Esber AL, Dear N, Reed D, Adamu Y, Tiamiyu AB, Mohammed SS, Kibuuka H, Maswai J, Owuoth J, Bahemana E, Ake JA, Polyak CS, Crowell TA; AFRICOS Study Group. Assessing the impact of HIV support groups on antiretroviral therapy adherence and viral suppression in the African cohort study. BMC Infect Dis. 2021 Jul 20;21(1):694. doi: 10.1186/s12879-021-06390-3. PMID: 34281502.
Wansom T, Muangnoicharoen S, Nitayaphan S, Kitsiripornchai S, Crowell TA, Francisco L, Gilbert P, Rwakasyaguri D, Dhitavat J, Li Q, King D, Robb ML, Smith K, Heger EA, Akapirat S, Pitisuttithum P, O'Connell RJ, Vasan S. Risk Factors for HIV sero-conversion in a high incidence cohort of men who have sex with men and transgender women in Bangkok, Thailand. EClinicalMedicine. 2021 Jul 17;38:101033. doi: 10.1016/j.eclinm.2021.101033. eCollection 2021 Aug. PMID: 34505031.
Copeland NK, Eller MA, Kim D, Creegan M, Esber A, Anne Eller L, Semwogerere M, Kibuuka H, Kiweewa F, Crowell TA, Polyak CS, Ake JA. Increased Inflammation and Liver Disease in HIV/HBV-coinfected Individuals. J Acquir Immune Defic Syndr. 2021 Jul 14. doi: 10.1097/QAI.0000000000002760. Online ahead of print. PMID: 34267057.
Yabes JM Jr, Schnarrs PW, Foster LB Jr, Scott PT, Okulicz JF, Hakre S. The 3 levels of HIV stigma in the United States military: perspectives from service members living with HIV. BMC Public Health. 2021 Jul 15;21(1):1399. doi: 10.1186/s12889-021-11462-9. PMID: 34266390.
Lewitus E, Sanders-Buell E, Bose M, O'Sullivan AM, Poltavee K, Li Y, Bai H, Mdluli T, Donofrio G, Slike B, Zhao H, Wong K, Chen L, Miller S, Lee J, Ahani B, Lepore S, Muhammad S, Grande R, Tran U, Dussupt V, Mendez-Rivera L, Nitayaphan S, Kaewkungwal J, Pitisuttithum P, Rerks-Ngarm S, O'Connell RJ, Janes H, Gilbert PB, Gramzinski R, Vasan S, Robb ML, Michael NL, Krebs SJ, Herbeck JT, Edlefsen PT, Mullins JI, Kim JH, Tovanabutra S, Rolland M. RV144 vaccine imprinting constrained HIV-1 evolution following breakthrough infection. Virus Evol. 2021 Jul 9;7(2):veab057. doi: 10.1093/ve/veab057. eCollection 2021. PMID: 34532060.
Adeyemi OA, Mitchell A, Shutt A, Crowell TA, Ndembi N, Kokogho A, Ramadhani HO, Robb ML, Baral SD, Ake JA, Charurat ME, Peel S, Nowak RG; TRUST/RV368 study group. Hepatitis B virus infection among men who have sex with men and transgender women living with or at risk for HIV: a cross sectional study in Abuja and Lagos, Nigeria. BMC Infect Dis. 2021 Jul 6;21(1):654. doi: 10.1186/s12879-021-06368-1. PMID: 34229613.
Muccini C, Pinyakorn S, Sirivichayakul S, Kroon E, Sacdalan C, Crowell TA, Trichavaroj R, Ananworanich J, Vasan S, Phanuphak N, Colby DJ; RV254 Study Group. Brief Report: Prevalence Trend of Transmitted Drug Resistance in a Prospective Cohort of Thai People With Acute HIV Infection. J Acquir Immune Defic Syndr. 2021 Aug 15;87(5):1173-1177. doi: 10.1097/QAI.0000000000002718. PMID: 34229330.
Komla E, Torres OB, Jalah R, Sulima A, Beck Z, Alving CR, Jacobson AE, Rice KC, Matyas GR. Effect of Preexisting Immunity to Tetanus Toxoid on the Efficacy of Tetanus Toxoid-Conjugated Heroin Vaccine in Mice. Vaccines (Basel). 2021 Jun 1;9(6):573. doi: 10.3390/vaccines9060573. PMID: 34205869.
Sei CJ, Rao M, Schuman RF, Daum LT, Matyas GR, Rikhi N, Muema K, Anderson A, Jobe O, Kroscher KA, Alving CR, Fischer GW. Conserved Influenza Hemagglutinin, Neuraminidase and Matrix Peptides Adjuvanted with ALFQ Induce Broadly Neutralizing Antibodies. Vaccines (Basel). 2021 Jun 25;9(7):698. doi: 10.3390/vaccines9070698. PMID: 34202178.
Olawore O, Crowell TA, Ketende SC, Ramadhani HO, Liu H, Ake JA, Kokogho A, Adebajo S, Charurat ME, Nowak RG, Baral SD; TRUST/RV368 Study Group. Individual and partnership characteristics associated with consistent condom use in a cohort of cisgender men who have sex with men and transgender women in Nigeria. BMC Public Health. 2021 Jun 30;21(1):1277. doi: 10.1186/s12889-021-11275-w. PMID: 34193101.
Goh OQ, Kroon E, Sacdalan C, Chan P, Crowell TA, Kanaprach R, Anonworanich J, Vasan S, Wu AW, Phanuphak N, Colby DJ. Persons living with HIV treated in acute HIV infection report good health-related quality of life in Thailand. AIDS Care. 2021 Jun 30:1-8. doi: 10.1080/09540121.2021.1944596. Online ahead of print. PMID: 34191663.
Gutman ES, Irvin TC, Morgan JB, Barrientos RC, Torres OB, Beck Z, Matyas GR, Jacobson AE, Rice KC. Synthesis and immunological effects of C14-linked 4,5-epoxymorphinan analogues as novel heroin vaccine haptens. RSC Chem Biol. 2021 Apr 19;2(3):835-842. doi: 10.1039/d1cb00029b. PMID: 34179783.
Li Y, Bai H, Sanders-Buell E, Dussupt V, Townsley S, Donofrio G, Bose M, O'Sullivan AM, Kibuuka H, Maganga L, Nitayaphan S, Kosgei J, Pitisuttithum P, Rerks-Ngarm S, Eller LA, Michael NL, Robb ML, Ake J, Vasan S, Tovanabutra S, Krebs SJ, Rolland M. Limited evidence for a relationship between HIV-1 glycan shield features in early infection and the development of neutralization breadth. J Virol. 2021 Jun 23:JVI0079721. doi: 10.1128/JVI.00797-21. Online ahead of print. PMID: 34160251.
Tunnage J, Yates A, Nwoga C, Sing'oei V, Owuoth J, Polyak CS, Crowell TA; RV393 Study Group. Hepatitis and tuberculosis testing are much less common than HIV testing among adults in Kisumu, Kenya: results from a cross-sectional assessment. BMC Public Health. 2021 Jun 15;21(1):1143. doi: 10.1186/s12889-021-11164-2. PMID: 34130663.
Paquin-Proulx D, Gunn BM, Alrubayyi A, Clark DV, Creegan M, Kim D, Kibuuka H, Millard M, Wakabi S, Eller LA, Michael NL, Schoepp RJ, Hepburn MJ, Hensley LE, Robb ML, Alter G, Eller MA. Associations Between Antibody Fc-Mediated Effector Functions and Long-Term Sequelae in Ebola Virus Survivors. Front Immunol. 2021 May 20;12:682120. doi: 10.3389/fimmu.2021.682120. eCollection 2021. PMID: 34093585.
Cai F, Chen WH, Wu W, Jones JA, Choe M, Gohain N, Shen X, LaBranche C, Eaton A, Sutherland L, Lee EM, Hernandez GE, Wu NR, Scearce R, Seaman MS, Moody MA, Santra S, Wiehe K, Tomaras GD, Wagh K, Korber B, Bonsignori M, Montefiori DC, Haynes BF, de Val N, Joyce MG, Saunders KO. Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates. PLoS Pathog. 2021 Jun 4;17(6):e1009624. doi: 10.1371/journal.ppat.1009624. Online ahead of print. PMID: 34086838.
Barrientos RC, Whalen C, Torres OB, Sulima A, Bow EW, Komla E, Beck Z, Jacobson AE, Rice KC, Matyas GR. Bivalent Conjugate Vaccine Induces Dual Immunogenic Response That Attenuates Heroin and Fentanyl Effects in Mice. Bioconjug Chem. 2021 Jun 2. doi: 10.1021/acs.bioconjchem.1c00179. Online ahead of print. PMID: 34076427.
Lu P, Guerin DJ, Lin S, Chaudhury S, Ackerman ME, Bolton DL, Wallqvist A. Immunoprofiling Correlates of Protection Against SHIV Infection in Adjuvanted HIV-1 Pox-Protein Vaccinated Rhesus Macaques. Front Immunol. 2021 May 11;12:625030. doi: 10.3389/fimmu.2021.625030. eCollection 2021. PMID: 34046030.
Vaillancourt M, Hubert A, Subra C, Boucher J, Bazié WW, Vitry J, Berrazouane S, Routy JP, Trottier S, Tremblay C, Jenabian MA, Benmoussa A, Provost P, Tessier PA, Gilbert C. Velocity Gradient Separation Reveals a New Extracellular Vesicle Population Enriched in miR-155 and Mitochondrial DNA. Pathogens. 2021 Apr 27;10(5):526. doi: 10.3390/pathogens10050526. PMID: 33925397.
Dear N, Duff E, Esber A, Parikh A, Iroezindu M, Bahemana E, Kibuuka H, Owuoth J, Maswai J, Crowell TA, Ake JA, Polyak CS. Transient reductions in HIV clinic attendance and food security during the COVID-19 pandemic for people living with HIV in four African countries. Clin Infect Dis. 2021 Apr 27:ciab379. doi: 10.1093/cid/ciab379. Online ahead of print. PMID: 33906235.
Semwogerere M, Dear N, Tunnage J, Reed D, Kibuuka H, Kiweewa F, Iroezindu M, Bahemana E, Maswai J, Owuoth J, Crowell TA, Ake JA, Polyak CS, Esber A; AFRICOS Study Group.Factors associated with sexually transmitted infections among care-seeking adults in the African Cohort Study. BMC Public Health. 2021 Apr 16;21(1):738. doi: 10.1186/s12889-021-10762-4. PMID: 33863295.
MalariaGEN, Ahouidi A, Ali M, Almagro-Garcia J, Amambua-Ngwa A, Amaratunga C, Amato R, Amenga-Etego L, Andagalu B, Anderson TJC, Andrianaranjaka V, Apinjoh T, Ariani C, Ashley EA, Auburn S, Awandare G, Ba H, Baraka V, Barry AE, Bejon P, Bertin GI, Boni MF, Borrmann S, Bousema T, Branch O, Bull PC, Busby GBJ, Chookajorn T, Chotivanich K, Claessens A, Conway D, Craig A, D'Alessandro U, Dama S, Day NP, Denis B, Diakite M, Djimdé A, Dolecek C, Dondorp AM, Drakeley C, Drury E, Duffy P, Echeverry DF, Egwang TG, Erko B, Fairhurst RM, Faiz A, Fanello CA, Fukuda MM, Gamboa D, Ghansah A, Golassa L, Goncalves S, Hamilton WL, Harrison GLA, Hart L, Henrichs C, Hien TT, Hill CA, Hodgson A, Hubbart C, Imwong M, Ishengoma DS, Jackson SA, Jacob CG, Jeffery B, Jeffreys AE, Johnson KJ, Jyothi D, Kamaliddin C, Kamau E, Kekre M, Kluczynski K, Kochakarn T, Konaté A, Kwiatkowski DP, Kyaw MP, Lim P, Lon C, Loua KM, Maïga-Ascofaré O, Malangone C, Manske M, Marfurt J, Marsh K, Mayxay M, Miles A, Miotto O, Mobegi V, Mokuolu OA, Montgomery J, Mueller I, Newton PN, Nguyen T, Nguyen TN, Noedl H, Nosten F, Noviyanti R, Nzila A, Ochola-Oyier LI, Ocholla H, Oduro A, Omedo I, Onyamboko MA, Ouedraogo JB, Oyebola K, Pearson RD, Peshu N, Phyo AP, Plowe CV, Price RN, Pukrittayakamee S, Randrianarivelojosia M, Rayner JC, Ringwald P, Rockett KA, Rowlands K, Ruiz L, Saunders D, Shayo A, Siba P, Simpson VJ, Stalker J, Su XZ, Sutherland C, Takala-Harrison S, Tavul L, Thathy V, Tshefu A, Verra F, Vinetz J, Wellems TE, Wendler J, White NJ, Wright I, Yavo W, Ye H. An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples. Wellcome Open Res. 2021 Feb 24;6:42. doi: 10.12688/wellcomeopenres.16168.1. eCollection 2021.PMID: 33824913.
Sing'oei V, Ochola J, Owuoth J, Otieno J, Rono E, Andagalu B, Otieno L, Nwoga C, Copeland NK, Lawlor J, Yates A, Imbach M, Crowell TA, Eller LA, Kamau E, Modjarrad K, Cowden J, Ake J, Robb ML, Polyak CS. Clinical laboratory reference values in adults in Kisumu County, Western Kenya; hematology, chemistry and CD4. PLoS One. 2021 Mar 30;16(3):e0249259. doi: 10.1371/journal.pone.0249259. eCollection 2021. PMID: 33784358.
Rolland M, Gilbert PB. Sieve analysis to understand how SARS-CoV-2 diversity can impact vaccine protection. PLoS Pathog. 2021 Mar 25;17(3):e1009406. doi: 10.1371/journal.ppat.1009406. eCollection 2021 Mar. PMID: 33765086.
Song H, Bose M, Pinyakorn S, Sanders-Buell E, O'Sullivan AM, Silas D, Trichavaroj R, Nuntapinit B, Pham PT, Akapirat S, Kroon E, de Souza M, Gramzinski R, Michael NL, Robb ML, Vasan S, Tovanabutra S, Ananworanich J. Dynamics of Human Immunodeficiency Virus-1 Genetic Diversification During Acute Infection. Open Forum Infect Dis. 2020 Sep 12;7(10):ofaa429. doi: 10.1093/ofid/ofaa429. eCollection 2020 Oct. PMID: 33748316.
Chan P, Colby DJ, Kroon E, Sacdalan C, Pinyakorn S, Paul R, Robb M, Valcour V, Ananworanich J, Marra C, Spudich S. Clinical and laboratory impact of concomitant syphilis infection during acute HIV. HIV Med. 2021 Mar 17. doi: 10.1111/hiv.13079. Online ahead of print. PMID: 33728759.
Jones MU, Esber AL, Dear N, Bahemana E, Kibuuka H, Iroezindu M, Maswai J, Owuoth J, Polyak CS, Ake JA, Crowell TA, Hickey PW; African Cohort Study (AFRICOS) Team. The pregnancy factor: the prevalence of depression among women living with HIV enrolled in the African Cohort Study (AFRICOS) by pregnancy status. Arch Womens Ment Health. 2021 Mar 8. doi: 10.1007/s00737-021-01117-4. Online ahead of print. PMID: 33683462.
Dussupt V, Modjarrad K, Krebs SJ. Landscape of Monoclonal Antibodies Targeting Zika and Dengue: Therapeutic Solutions and Critical Insights for Vaccine Development. Front Immunol. 2021 Feb 4;11:621043. doi: 10.3389/fimmu.2020.621043. eCollection 2020. PMID: 33664734.
Livingstone MC, Bitzer AA, Giri A, Luo K, Sankhala RS, Choe M, Zou X, Dennison SM, Li Y, Washington W, Ngauy V, Tomaras GD, Joyce MG, Batchelor AH, Dutta S. In vitro and in vivo inhibition of malaria parasite infection by monoclonal antibodies against Plasmodium falciparum circumsporozoite protein (CSP). Sci Rep. 2021 Mar 5;11(1):5318. doi: 10.1038/s41598-021-84622-x. PMID: 33674699.
Townsley SM, Donofrio GC, Jian N, Leggat DJ, Dussupt V, Mendez-Rivera L, Eller LA, Cofer L, Choe M, Ehrenberg PK, Geretz A, Gift S, Grande R, Lee A, Peterson C, Piechowiak MB, Slike BM, Tran U, Joyce MG, Georgiev IS, Rolland M, Thomas R, Tovanabutra S, Doria-Rose NA, Polonis VR, Mascola JR, McDermott AB, Michael NL, Robb ML, Krebs SJ. B cell engagement with HIV-1 founder virus envelope predicts development of broadly neutralizing antibodies. Cell Host Microbe. 2021 Feb 26:S1931-3128(21)00046-9. doi: 10.1016/j.chom.2021.01.016. Online ahead of print. PMID: 33662277.
Karch CP, Burkhard P, Matyas GR, Beck Z. The diversity of HIV-1 fights against vaccine efficacy: how self-assembling protein nanoparticle technology may fight back. Nanomedicine (Lond). 2021 Mar 10. doi: 10.2217/nnm-2020-0450. Online ahead of print. PMID: 33715403.
Bright B, Babalola CP, Sam-Agudu NA, Onyeaghala AA, Olatunji A, Aduh U, Sobande PO, Crowell TA, Tebeje YK, Phillip S, Ndembi N, Folayan MO. COVID-19 preparedness: capacity to manufacture vaccines, therapeutics and diagnostics in sub-Saharan Africa. Global Health. 2021 Mar 3;17(1):24. doi: 10.1186/s12992-021-00668-6. PMID: 33658050.
Hsu DC, Schuetz A, Imerbsin R, Silsorn D, Pegu A, Inthawong D, Sopanaporn J, Visudhiphan P, Chuenarom W, Keawboon B, Shi W, Robb ML, Mascola JR, Geleziunas R, Koup RA, Barouch DH, Michael NL, Vasan S. TLR7 agonist, N6-LS and PGT121 delayed viral rebound in SHIV-infected macaques after antiretroviral therapy interruption. PLoS Pathog. 2021 Feb 18;17(2):e1009339. doi: 10.1371/journal.ppat.1009339. Online ahead of print. PMID: 33600506.
Lima NS, Moon D, Darko S, De La Barrera RA, Lin L, Koren MA, Jarman RG, Eckels KH, Thomas SJ, Michael NL, Modjarrad K, Douek DC, Trautmann L. Pre-existing Immunity to Japanese Encephalitis Virus Alters CD4 T Cell Responses to Zika Virus Inactivated Vaccine. Front Immunol. 2021 Feb 24;12:640190. doi: 10.3389/fimmu.2021.640190. eCollection 2021. PMID: 33717194.
Tola M, Habib RO, Sylvia A, Crowell TA, Rebecca NG, Charurat ME, Dakum P, Ndembi N. Field evaluation of HIV-1 viral load monitoring in adults and children receiving antiretroviral treatment in Nigeria by dried blood spot testing with RealTime HIV-1 on m2000. J Clin Virol. 2021 Feb;135:104694. doi: 10.1016/j.jcv.2020.104694. Epub 2020 Nov 25. PMID: 33476928.
Silva de Castro I, Gorini G, Mason R, Gorman J, Bissa M, Rahman MA, Arakelyan A, Kalisz I, Whitney S, Becerra-Flores M, Ni E, Peachman K, Trinh HV, Read M, Liu MH, Van Ryk D, Paquin-Proulx D, Shubin Z, Tuyishime M, Peele J, Ahmadi MS, Verardi R, Hill J, Beddall M, Nguyen R, Stamos JD, Fujikawa D, Min S, Schifanella L, Vaccari M, Galli V, Doster MN, Liyanage NPM, Sarkis S, Caccuri F, LaBranche C, Montefiori DC, Tomaras GD, Shen X, Rosati M, Felber BK, Pavlakis GN, Venzon DJ, Magnanelli W, Breed M, Kramer J, Keele BF, Eller MA, Cicala C, Arthos J, Ferrari G, Margolis L, Robert-Guroff M, Kwong PD, Roederer M, Rao M, Cardozo TJ, Franchini G. Anti-V2 antibodies virus vulnerability revealed by envelope V1 deletion in HIV vaccine candidates. iScience. 2021 Jan 9;24(2):102047. doi: 10.1016/j.isci.2021.102047. eCollection 2021 Feb 19. PMID: 33554060.
Dearlove B, Tovanabutra S, Owen CL, Lewitus E, Li Y, Sanders-Buell E, Bose M, O'Sullivan AM, Kijak G, Miller S, Poltavee K, Lee J, Bonar L, Harbolick E, Ahani B, Pham P, Kibuuka H, Maganga L, Nitayaphan S, Sawe FK, Kim JH, Eller LA, Vasan S, Gramzinski R, Michael NL, Robb ML, Rolland M; RV217 Study Team. Factors influencing estimates of HIV-1 infection timing using BEAST. PLoS Comput Biol. 2021 Feb 1;17(2):e1008537. doi: 10.1371/journal.pcbi.1008537. Online ahead of print. PMID: 33524022.
Muccini C, Crowell TA, Pinyakorn S, Kroon E, Sacdalan C, Ananworanich J, Vasan S, Phanuphak N, Colby DJ; RV254 Study Group. Brief Report: Syphilis Incidence and Effect on Viral Load, CD4, and CD4/CD8 Ratio in a Thai Cohort of Predominantly Men Who Have Sex With Men Living With HIV. J Acquir Immune Defic Syndr. 2021 Feb 1;86(2):219-223. doi: 10.1097/QAI.0000000000002542. PMID: 33433124.
Schneider CG, Taylor JA, Sibilo MQ, Miura K, Mallory KL, Mann C, Karch C, Beck Z, Matyas GR, Long CA, Bergmann-Leitner E, Burkhard P, Angov E. Orientation of Antigen Display on Self-Assembling Protein Nanoparticles Influences Immunogenicity. Vaccines (Basel). 2021 Jan 29;9(2):103. doi: 10.3390/vaccines9020103. PMID: 33572803.
Crowell TA, Fast PE, Bekker LG, Sanders EJ. Response to: "Inclusion as Illusion: Erasing Transgender Women in Research with MSM". J Int AIDS Soc. 2021 Jan;24(1):e25662. doi: 10.1002/jia2.25662. PMID: 33496371.
Garcia-Bates TM, Palma ML, Anderko RR, Hsu DC, Ananworanich J, Korber BT, Gaiha GD, Phanuphak N, Thomas R, Tovanabutra S, Walker BD, Mellors JW, Piazza PA, Kroon E, Riddler SA, Michael NL, Rinaldo CR, Mailliard RB; I4C and RV254 Study Groups. Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes. EBioMedicine. 2021 Jan 12;63:103175. doi: 10.1016/j.ebiom.2020.103175. Online ahead of print. PMID: 33450518.
Lee EH, Ganesan K, Khamadi SA, Meribe SC, Njeru D, Adamu Y, Magala F, Crowell TA, Akom E, Agaba P, Desai P, Hamm T, Teyhen D, Ake JA, Polyak CS, Shaffer D, Sawe F, Hickey PW. Attaining 95-95-95 through Implementation Science: 15 Years of Insights and Best Practices from the Walter Reed Army Institute of Research's Implementation of the U.S. President's Emergency Plan for AIDS Relief. Am J Trop Med Hyg. 2021 Jan;104(1):12-25. doi: 10.4269/ajtmh.20-0541. PMID: 33241783.