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November 9, 2016
Investigational HIV Therapeutic Vaccine Approach Helps Control SIV in Preclinical Studies

Researchers have found that an investigational treatment combining a therapeutic vaccine and an immune stimulator improves virologic control and delays viral rebound following the discontinuation of antiretroviral therapy (ART) in non-human primates infected with SIV, the simian form of HIV.

The proof-of-concept study examined the combined effects of therapeutic vaccination with an...

November 7, 2016
Human Trials Begin for Army-Developed Zika Purified Inactivated Virus (ZPIV) Vaccine

The Walter Reed Army Institute of Research (WRAIR) began vaccinations today in a Phase 1 human clinical trial to test the safety and immunogenicity of the Zika purified inactivated virus (ZPIV) vaccine.

Seventy-five healthy adults will be recruited to participate in the trial at WRAIR’s Clinical Trial Center in Silver Spring, Md. Given the concerns for immune enhancement with other...

November 3, 2016
MHRP Scientists and Collaborators Detect Declining Trend in Transmitted Drug Resistance in Acute HIV Infection Cohort

A recent study conducted by researchers from the U.S. Military HIV Research Program (MHRP) and the Thai Red Cross has shown that the prevalence of transmitted drug resistance (TDR) has declined in a cohort of individuals with acute HIV infection in Bangkok, Thailand. Findings were published earlier this week in the Journal of the International AIDS Society.

Drug resistant HIV can arise...

October 31, 2016
New MHRP PEPFAR-funded Study to Examine Malaria and TB HIV Co-infection in Kenyan Defence Forces

This week, the U.S. Military HIV Research Program (MHRP) began a new research study in Kenya in collaboration with the Kenyan Defence Forces (KDF).

The study, called RV292, will assess the prevalence of HIV-1, HIV/tuberculosis co-infection and malaria among the active duty within the Kenyan Defence Forces (KDF). Research staff opened enrollment for the study at multiple sites in Kenya...

October 13, 2016
MHRP and Collaborators at HIV Research for Prevention (HIVR4P) 2016

MHRP researchers and collaborators are scheduled to speak and present at the 2016 HIVR4P conference taking place October 17-21 in Chicago.



September 30, 2016
Experts Identify Challenges to Fast-Track Development of Zika Vaccine

Zika vaccine development is advancing rapidly thanks to cross-sector research and development collaboration along with promising preclinical findings that demonstrate an effective vaccine is feasible.

However, to maintain this momentum and ultimately develop, license, and deploy a vaccine capable of impacting the current epidemic, collaborators will need to anticipate and address...

August 22, 2016
HIV Infant Tracking System (HITSystem) Improves Early Diagnosis Outcomes in Tanzania

There have been significant advances in the management of HIV/AIDS over the years. However, the management of HIV-exposed infants (HEI) has been hampered by challenges of tracking the testing process and communication of results to the mothers for initiation of care in a timely manner. Early infant diagnosis (​​EID) of HIV infection is essential in ensuring timely initiation of antiretroviral...

August 3, 2016
Vaccine Candidates Protect Against Zika Virus in Rhesus Monkeys

The Walter Reed Army Institute of Research (WRAIR), in collaboration with the Beth Israel Deaconess Medical Center (BIDMC), has completed a second round of preclinical studies on a promising Zika vaccine candidate and found it to completely protect rhesus monkeys from experimental infection with Zika virus.

WRAIR researchers and partners recently reported the protective efficacy of a...

August 1, 2016
Early Antiretroviral Therapy Dramatically Reduces HIV DNA Set Point

A team of researchers, led by Drs. Merlin Robb and Jintanat Ananworanich of the U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research, has found that when antiretroviral therapy (ART) is initiated during early acute HIV infection, it can significantly reduce total HIV DNA levels in the body, which may have implications for the goal of achieving long-term HIV...

July 13, 2016
MHRP Scientists and Collaborators Presenting at AIDS 2016

The AIDS 2016 conference will be held in Durban, South Africa, July 18-22. Read on to learn more about MHRP oral and poster presentations and well as special sessions that include MHRP speakers.

Saturday, July 16 —Towards and HIV Cure: Engaging the Community workshop, 9:00 a.m. Dr. Jintanat Ananworanich will participate in a panel discussion at this workshop on the research priorities...