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March 17, 2011
Study Finds HIV Vaccine Influences the Genetic Makeup of the Virus
MHRP’s molecular epidemiologists played a key role on a research team that analyzed the HIV-1 genome sequences from infected volunteers in the Step HIV vaccine trial. Findings indicate that that although ineffective at preventing infection, the vaccine impacted the genetic makeup of the virus that infected the volunteers. Results were published Feb. 27 in Nature Medicine.
After...
March 10, 2011
Collaborative Efforts to Combat Malaria in Tanzania
Quality diagnostic capabilities are critical to malaria control efforts in Tanzania. There is an urgent need to improve diagnostic infrastructure and develop local technical capacity for malaria microscopy and rapid diagnostic tests (mRDT’s) diagnosis.
WRAIR’s HIV site in Tanzania, Walter Reed Program-Tanzania (WRP-T), is working closely with the Malaria Program at WRAIR to build much...
February 11, 2011
Caring for the Children Left Behind by HIV
In Southwestern Tanzania, just steps from the Malawi border lies the bustling port town of Kyela, one of eight districts in the Mbeya region. A bustling commercial hub, Kyela endures an HIV prevalence rate well above the national average, which leaves a staggering number of children orphaned and vulnerable. In Kyela, approximately 7,100 children have been orphaned following the devastating...
January 19, 2011
Laboratory Training Program Brings Together MHRP, Nigerian Military and the U.S. Public Health Service
In September, 2010, eight U.S. Public Health Service (PHS) officers were deployed to MHRP’s site in Lagos, Nigeria to participate in a malaria diagnostics and laboratory capacity building training exercise. This program provided hands-on education and practical experience in the field, enhancing their readiness and proficiency.
This five-day course in Nigeria consisted of didactic and...
January 11, 2011
Researchers Identify New Generic Vaccine Adjuvants
MHRP scientists have identified three highly effective, non-proprietary and easily manufactured adjuvants that proved safe and more potent than a widely used adjuvant in commercial vaccines for inducing antibodies to anthrax protective antigen. Adjuvants are vaccine components designed to stimulate the immune system, therefore enhancing the body’s ability to protect against diseases. The study...
December 16, 2010
Risk of Acquiring a Transfusion-Transmitted Infection Found to be Low for Military Personnel Who Receive Blood on the Battlefield
A new study suggests that the risk for U.S. Military personnel of contracting an infection following an emergency blood transfusion is low considering screening procedures are limited on the battlefield. This study was published online on October 7, 2010 in Transfusion.
Researchers analyzed available pre- and post-transfusion samples from the 761 U.S. Service members who received a...
December 8, 2010
New Study Shows a Novel Antibody That Binds to Intracellular Lipids and Inhibits HIV Infection
MHRP scientists have developed a monoclonal antibody that binds solely to lipids located inside cells but has the capability to neutralize HIV. This research is published in the October 26, 2010 online issue of Biochemical and Biophysical Research Communications.
Investigators compared WR321, a non-human monoclonal IgG antibody that binds to phosphoinositide lipids, developed by Dr....
December 1, 2010
2010 MHRP World Aids Day Activities
United States
Kenya
Tanzania
Uganda
Thailand
US - Washington, DC
Event: Partnering for an HIV Free World
Date: 01 December 2010
Location: Walter Reed Army Institute of Research (WRAIR), Silver Spring, MD, 10:00 am - 3:00 pm
Join WRAIR for a series of talks to commemorate World AIDS Day. There will be a special focus on...
November 23, 2010
iPrEx study on Pre-Exposure Prophylaxis (PrEP) Shows Some Effectiveness in Preventing HIV
Study results, published in today’s online issue of the New England Journal of Medicine, show that antiretroviral medications taken orally on a daily basis by men who have sex with men can provide partial protection from HIV infection.
The study included 2,499 volunteers in high-risk populations in Brazil, Ecuador, Peru, South Africa, Thailand and the U.S. The study participants were...
November 23, 2010
iPrEx study on Pre-Exposure Prophylaxis (PrEP) Shows Some Effectiveness in Preventing HIV
Study results, published in today’s online issue of the New England Journal of Medicine, show that antiretroviral medications taken orally on a daily basis by men who have sex with men can provide partial protection from HIV infection.
The study included 2,499 volunteers in high-risk populations in Brazil, Ecuador, Peru, South Africa, Thailand and the U.S. The study participants were...