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October 27, 2010
Researchers Identify Gene Variant Associated with Protection from HIV in Tanzania
A gene variant found almost exclusively in East Africa may provide protection from acquiring HIV-1 and inhibit the progression of the disease in those already infected. Researchers at the U.S. Military HIV Research Program (MHRP) reported the findings in the Journal of Infectious Diseases.
In collaboration with researchers from the University of Munich, Germany, and the Mbeya Medical...
October 14, 2010
OCTANE Study Influences Revision of WHO Guidelines for Treating Some HIV-Infected Women
Findings from a study, which appear in the October 14, 2010 New England Journal of Medicine, helped influence the World Health Organization (WHO) to change its guidelines this year for the treatment of HIV-infected women who receive a single dose of the antiretroviral drug nevirapine to prevent HIV transmission to their babies. The study demonstrated that the single dose of nevirapine used to...
October 13, 2010
MHRP Scientists Take Part in AIDS Vaccine 2010 Conference in Atlanta
More than 1,000 HIV scientists, clinicians, epidemiologists and public health experts convened in Atlanta for AIDS Vaccine 2010. This year, the conference marked its 10th anniversary of providing an international platform for investigators to share and exchange ideas and research.
Much of the discussion at the meeting surrounded RV144 and correlates analysis that is currently underway....
September 28, 2010
Human Clinical Trial of DNA-MVA HIV Vaccine Candidate Begins
A Phase I study, called RV262, recently began to evaluate a combination DNA prime/MVA vector boost vaccine regimen that was developed to protect against diverse subtypes of HIV-1 prevalent in North America, Europe, Africa and South America.
The National Institute of Allergy and Infectious Diseases (NIAID), part of the U.S. National Institutes of Health (NIH), is sponsoring the study,...
September 24, 2010
RV144: Further Research is Underway
In September 2009, the Army announced that a clinical trial in Thailand showed, for the first time, that a vaccine is able to reduce the risk of HIV infection in humans. Although the results from this study were modest, they are providing a great deal of information to inform the field of HIV vaccine research.
Already, RV144 has raised several interesting hypotheses about the types of...
September 22, 2010
Innovative "Moonlight" HIV Counseling and Testing
Staff at the Kericho Youth Centre (KYC), an NGO supported by the Walter Reed Project – Kenya (WRP), found an inventive and highly successful way to provide training, HIV testing and counseling services to high-risk youth including commercial sex workers and their clients—by going where they go under the cover of darkness.
Along the major highway that runs through the Kericho District in...
September 16, 2010
USAMRMC Wins Research and Development Lab of the Year
Deputy Assistant Secretary of the Army Marilyn Miller Freeman announced Friday that Medical Research and Materiel Command (MRMC) was chosen as the 2010 Research and Development Laboratory of the Year (small lab). The Department of the Army Research and Development Laboratory of the Year Awards program is an annual event in which Army laboratories are evaluated on technical...
September 7, 2010
Comprehensive New Framework to Speed and Enhance HIV Research
A new vision to accelerate the search for an HIV vaccine, developed by the Council of the Global HIV Vaccine Enterprise with the participation of hundreds of scientists, policy-makers, funders and advocates worldwide, was published today in Nature Medicine.
The Plan, the product of an 18-month collaborative process, was developed by the Global HIV Vaccine Enterprise, a unique alliance...
August 18, 2010
PEPFAR Program Representatives Gather in Kenya to Share Successes and Plan for the Future
Representatives from MHRP’s PEPFAR program convened in Kisumu, Kenya 13-15 July 2010 to review the collective progress made over the past year and to plan for the upcoming year. PEPFAR staff from Tanzania, Kenya, Uganda, and Nigeria and MHRP staff from Maryland, USA participated in this annual gathering.
Dr. Tiffany Hamm, Deputy Director for PEPFAR at MHRP, presented an overview of the...
August 9, 2010
Researchers Determine Factors Associated with Elevated Viral Load Setpoint in Sub-Saharan Africa
Gender, genetic background, and multiple HIV infections all factor into the level of virus found in the blood at viral load setpoint (VLS) of HIV-infected individuals in Sub-Saharan Africa according to a recent study published in the Journal of Acquired Immune Deficiency Syndrome (JAIDS). The study was led by Dr. Michael Hoelscher with the Mbyea Medical Research Programme, a partner of the...