WRAIR's Diagnostics and Countermeasures Branch oversees all HIV testing for the Army and serves as the Tri-Service Reference Laboratory
Specimen Testing
If you are a DoD site wanting to submit specimens to the HIV Diagnostics & Reference Laboratory (HDRL) for testing, please contact us at wrairhdrl@hivresearch.org to access test request forms, individual test specifications, and testing algorithms (PDF format).
Specimen Submission Guidelines (2025)
Test Specifications
Serology
- HIV Combo Ag/Ab EIA Test Specification (2025)
- HIV-1 Western Blot Supplemental Test Specification (2025)
- Geenius HIV 1/2 Supplemental Test Specification (2025)
- Hepatitis B Surface Antigen (HBsAg) Confirmatory Assay Test Specification (2025)
Molecular
- Hologic Panther HIV-1 Quant Dx Test Specifications in Plasma (2025)
- Hologic Panther HCV Quant Dx Test Specifications (2025)
- Sentosa SQ HIV-1 Genotyping Assay Test Specification (2025)
- HIV-1 TNA PCR HIV-2 TNA PCR Test Specifications (2025)
- Hologic Panther HIV-1 Quant Dx Test Specifications – Cerebral Spinal Fluid (CSF) (2025)
- Hologic Panther HIV-1 Quant Dx Test Specifications in Serum (2025)
Test Request Forms
- HDRL Serology Clinical Test Request Form (2025)
- HIV Verification Algorithm Test Request Form - CONUS sites only (2025)
- Molecular Aptima HCV Qualitative/Quantitative Dx Test Request Form (2025)
- Molecular Aptima HIV-1 Qualitative/Quantitative Dx Test Request (2025)
- Drug Resistance Test Request Form (2025)
- Vaccine Induced Sero-Reactivity Test Request Form (2025)
- Hepatitis B Surface Antigen Test Request Form (2025)
- HIV Verification Algorithm Test Request Form - OCONUS (2025)
- HIV-1 TNA PCR HIV -2 TNA PCR TEST Request Form (2025)
- Molecular Aptima HIV-1 Quantitative Dx in CSF Test Request Form (2025)
- Special Request Molecular Aptima HIV-1 Quantitative Dx Test Request Form (Serum) (2025)
Molecular HIV-1 Viral Load (Quant)/Drug Resistance Test Request Form (2025)
Test Algorithms
- Acute HIV Infection PreP Algorithm MAR 2025
- HDRL US Army HIV Algorithm MAR 2025
- Contractor HDRL US Army HIV Algorithm MAR 2025
POC Forms
- HDRL Point of Contact Form - Results Reporting (2025)
- HDRL Point of Contact Form - Notification & Follow-Up (2025)
Packing & Shipping
- Packaging and Shipment of Specimens
- Verification Specimen Kit Instructions (CONUS sites only)
- Verification Kit Packing Instructions
Certificates
Historical Changes
- Summary of Changes (July 2025)
- Summary of Changes (July 2023)
- Summary of Changes (February 2022)
- Summary of Changes (August 2021)
- Summary Of Changes (April 2019)
- HDRL SSG Update Memo_Signed (April 2019)
- HDRL SSG Update Memo_JUN17 (June 2017)
- Memo re: Modification of HDRL Testing, Effective December 1, 2016(December 2016)
- Summary of Changes (July 2015)
- Specimen Submission Guidelines (July 2015)
- Memo re: Modifications to HDRL's HIV 1/2 Rapid Testing Interpretations (March 3, 2015)
- Memo re: Availability of ViroSeq HIV-1 Integrase Genotype Assay (July 7, 2015)
- Memo re: Changes to Submission Guideline (March 23, 2015)